Endothelins [endoteliny]
- Terms
-
endotelin
-
Endothelin
Endothelium-Derived Vasoconstrictor Factors
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
- Annotation
- general or unspecified; prefer specifics
- DUI
- D016232 MeSH Browser
- CUI
- M0024788
- Previous indexing
- Peptides (1966-1990)
- History note
- 91
- Public note
- 91
Allowable subheadings
- AD
- administration & dosage 11
- AE
- adverse effects 10
- AG
- agonists 3
- AN
- analysis 17
- AI
- antagonists & inhibitors 28
- BI
- biosynthesis 3
- BL
- blood 41
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 6
- CL
- classification 3
- DF
- deficiency 1
- DE
- drug effects 1
- EC
- economics
- GE
- genetics 8
- HI
- history
- IM
- immunology 2
- IP
- isolation & purification 1
- ME
- metabolism 17
- PK
- pharmacokinetics
- PD
- pharmacology 19
- PH
- physiology 39
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 9
- TO
- toxicity
- UR
- urine
BQ 3020 Chemical MeSH Browser
Cys(11)-Cys(15)-endothelin-1 (11-21) Chemical MeSH Browser
IRL 1720 Chemical MeSH Browser
N(epsilon)-9-azidobenzoyliodoendothelin-1 Chemical MeSH Browser
big endothelin-1 (19-37), Phe(22)- Chemical MeSH Browser
big endothelin-1(16-38), valine(22)- Chemical MeSH Browser
big-endothelin (1-22) Chemical MeSH Browser
big-endothelin (16-32) Chemical MeSH Browser
endothelin (16-21) Chemical MeSH Browser
endothelin (16-21) amide Chemical MeSH Browser
endothelin 1, Ala(1,15)- Chemical MeSH Browser
endothelin 1, Ala(1,3,11,15)- Chemical MeSH Browser
endothelin 1, Ala(3,11)- Chemical MeSH Browser
endothelin 1, Dpr(1)-Asp(15)- Chemical MeSH Browser
endothelin, Nle(7)- Chemical MeSH Browser
endothelin-1,2-6-keto-PGF1-alpha Chemical MeSH Browser
endothelin7-21(Leu7,Aib11,Cys(Acm)15) Chemical MeSH Browser
preproendothelin 2 Chemical MeSH Browser
preproendothelin-3 Chemical MeSH Browser
proendothelin 2 Chemical MeSH Browser
proendothelin 3 Chemical MeSH Browser
proendothelin-1 (22-39) Chemical MeSH Browser
proendothelin-1 (31-38) Chemical MeSH Browser
sovateltide Chemical MeSH Browser