Apelin [apelin]

topical
4
Definition

A 77 amino acid secreted endogenous ligand for the angiotensin II receptor-like 1 protein (APELIN RECEPTOR) that is proteolytically cleaved into four smaller peptides: Apelin-36, Apelin-31, Apelin-28, and Apelin-13. It inhibits entry of HIV into cells that express both APJ and CD4 ANTIGEN and is highly expressed in breast milk, where it may modulate the neonatal immune response.

DUI
D000073861 MeSH Browser
CUI
M000624130
Previous indexing
Carrier Proteins (1998-2017); Intercellular Signaling Peptides and Proteins (2006-2017)
History note
2018
Public note
2018

D Chemicals and Drugs
D12.644 Peptides 1 382
D12.644.276.024 Adipokines 138
D12.644.276.074 Agouti-Related Protein 9
D12.644.276.100 Angiogenic Proteins 10
D12.644.276.150 Apelin 4
D12.644.276.374 Cytokines 2 154
D12.644.276.382 EGF Family of Proteins 7
D12.644.276.390 Endothelial Growth Factors 58
D12.644.276.400 Endothelins 184
D12.644.276.500 Ephrins 1
D12.644.276.624 Fibroblast Growth Factors 120
D12.644.276.671 Hedgehog Proteins 73
D12.644.276.742 Insulin-Like Peptides 1
D12.644.276.812 Kinins 37
D12.644.276.836 Kisspeptins 6
D12.644.276.854 Midkine 3
D12.644.276.857 Myokines
D12.644.276.860 Nerve Growth Factors 70
D12.644.276.917 Progranulins 2
D12.644.276.923 Semaphorins 4
D12.644.276.930 Serrate-Jagged Proteins 1
D12.644.276.942 Slit Homolog 2 Protein
D23.529.024 Adipokines 138
D23.529.100 Angiogenic Proteins 10
D23.529.134 Apelin 4
D23.529.168 B7 Antigens 3
D23.529.374 Cytokines 2 154
D23.529.400 Endothelins 184
D23.529.500 Ephrins 1
D23.529.671 Hedgehog Proteins 73
D23.529.812 Kinins 37
D23.529.831 Midkine 3
D23.529.841 Myokines
D23.529.850 Nerve Growth Factors 70
D23.529.917 Progranulins 2
D23.529.923 Semaphorins 4
D23.529.984 Wnt Proteins 57

APLN protein, human Chemical MeSH Browser

Apln protein, mouse Chemical MeSH Browser

Apln protein, rat Chemical MeSH Browser