Agouti Signaling Protein [signální protein aguti]
- Terms
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signální protein agouti
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Agouti Protein
Agouti Switch Protein
ASIP Protein
A secreted protein of approximately 131 amino acids (depending on species) that regulates the synthesis of eumelanin (brown/black) pigments in MELANOCYTES. Agouti protein antagonizes the signaling of MELANOCORTIN RECEPTORS and has wide distribution including ADIPOSE TISSUE; GONADS; and HEART. Its overexpression in agouti mice results in uniform yellow coat color, OBESITY, and metabolic defects similar to type II diabetes in humans.
- DUI
- D054366 MeSH Browser
- CUI
- M0214413
- Previous indexing
- Intercellular Signaling Peptides and Proteins (1994-2007)
- History note
- 2008 (1993)
- Public note
- 2008; AGOUTI PROTEIN was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 1993-2007
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
ASIP protein, human Chemical MeSH Browser
Asip protein, rat Chemical MeSH Browser
a protein, mouse Chemical MeSH Browser