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Total synthesis of the potent antifungal agents bengazole C and E
Álvaro Enríquez-García and Steven V. Ley
Collection of Czechoslovak Chemical Communications.
2009 ;
74 (6) :
887-900.
Jazyk angličtina Země Česko
Perzistentní odkaz
https://www.medvik.cz/link/bmc09004750
Online
NLK
ProQuest Central
od 2005-01-01 do 2011
- MeSH
- antifungální látky chemická syntéza MeSH
- financování organizované MeSH
- oxazoly izolace a purifikace MeSH
- Porifera chemie MeSH
The bengazoles are marine natural products with unique structure, containing two oxazole rings flanking a single carbon. They show very potent antifungal activity. The total syntheses of bengazole C and E are described following a convergent route which involves diastereoselective cycloaddition of an appropriately substituted nitrile oxide with a butane-1,2-diacetal-protected alkenediol as the key step.
Bibliografie atd.
Lit.: 7
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