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A high-power laser-driven source of sub-nanosecond soft X-ray pulses for single-shot radiobiology experiments
M Davidkova, L Juha, M Bittner, S Koptyaev, V Hajkova, J Krasa, M Pfeifer, V Stisova, A Bartnik, H Fiedorowicz, J Mikolajczyk, L Ryc, L Pina, M Horvath, D Babankova, J Cihelka, S Civis
Language English Country United States
Document type Evaluation Study
- MeSH
- Equipment Failure Analysis MeSH
- Radiation Dosage MeSH
- Equipment Design MeSH
- Lasers MeSH
- Nanotechnology methods instrumentation MeSH
- Specimen Handling methods instrumentation MeSH
- Plasmids chemistry drug effects MeSH
- DNA Damage radiation effects MeSH
- Radiobiology methods instrumentation MeSH
- X-Rays MeSH
- Research instrumentation MeSH
- Research Design MeSH
- Publication type
- Evaluation Study MeSH
A large-scale, double-stream gas puff target has been illuminated by sub-kJ, near-infrared (NIR) focused laser pulses at the PALS facility (Prague Asterix Laser System) to produce high-energy pulses of soft X rays from hot, dense plasma. The double-puff arrangement ensures high gas density and conversion efficiency from NIR to X rays approaching that typical for solid targets. In addition, its major advantage over solid targets is that it is free of debris and has substantially suppressed charged-particle emission. The X-ray emission characteristics of the source were determined for a range of gases that included krypton, xenon, N(2), CO and N(2)-CO. A demonstrated application of the xenon-based source is a single-shot damage induction to plasmid DNA. The yields of single-strand breaks (SSBs) and double-strand breaks (DSBs) were determined as a function of energy fluence adjusted by varying distance of sample from the source and thickness of aluminum filters.
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- $a Davídková, Marie. $7 stk2007383287
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- $a A high-power laser-driven source of sub-nanosecond soft X-ray pulses for single-shot radiobiology experiments / $c M Davidkova, L Juha, M Bittner, S Koptyaev, V Hajkova, J Krasa, M Pfeifer, V Stisova, A Bartnik, H Fiedorowicz, J Mikolajczyk, L Ryc, L Pina, M Horvath, D Babankova, J Cihelka, S Civis
- 314 __
- $a Department of Radiation Dosimetry, Institute of Nuclear Physics, Academy of Sciences of the Czech Republic, 180 86, Prague 8, Czech Republic. davidkova@ujf.cas.cz
- 520 9_
- $a A large-scale, double-stream gas puff target has been illuminated by sub-kJ, near-infrared (NIR) focused laser pulses at the PALS facility (Prague Asterix Laser System) to produce high-energy pulses of soft X rays from hot, dense plasma. The double-puff arrangement ensures high gas density and conversion efficiency from NIR to X rays approaching that typical for solid targets. In addition, its major advantage over solid targets is that it is free of debris and has substantially suppressed charged-particle emission. The X-ray emission characteristics of the source were determined for a range of gases that included krypton, xenon, N(2), CO and N(2)-CO. A demonstrated application of the xenon-based source is a single-shot damage induction to plasmid DNA. The yields of single-strand breaks (SSBs) and double-strand breaks (DSBs) were determined as a function of energy fluence adjusted by varying distance of sample from the source and thickness of aluminum filters.
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- $a Cihelka, Jaroslav. $7 _BN007289
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- $a Civiš, Svatopluk. $7 _BN007290
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