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Účinnost rTTMS u OCD neodpovídající na SSRI
[Efficacy of rTMS in OCD noresponders to SSRI]
Praško Ján, Bareš M., Horáček J., Kopeček M., Novák T., Pašková B., Tišlerová B., Záleský R.
Status not-indexed Language Czech Country Czech Republic
Document type Abstracts
Grant support
NR9323
MZ0
CEP Register
Digital library NLK
Full text - Část
Source
- Keywords
- obsessive compulsive disorder, antidepressants, pharmacoresistance, rTMS,
- Publication type
- Abstracts MeSH
The aim of the ran¬domized, double-blind, sham control- led study was to compare the 2 and 4 week efficacy of the 10 sessions rTMS with sham rTMS in SSRIs resistant OCD patient. Thirty seven patients were randomly assigned to either active rTMS or to sham. Active rTMS with the frequency of 1 Hz at 110 % of motor threshold was administered over the left dorso-lateral prefrontal cortex. The same time schedule has been used for the sham administration. Thirty four patients finished the study, three patients dropped out at the beginning. Psychopathology was assessed by CGI, HAMA, Y-BOCS, and BAI by an indepen¬dent reviewer. Both groups improved but the treatment effect did not differ between them.
Efficacy of rTMS in OCD noresponders to SSRI
14. celostátní konference biologické psychiatrie s mezinárodní účastí "Stálost a proměny biologické psychiatrie", Luhačovice, 10.-13. června 2009
Bibliography, etc.Lit.: 4
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- $a The aim of the ran¬domized, double-blind, sham control- led study was to compare the 2 and 4 week efficacy of the 10 sessions rTMS with sham rTMS in SSRIs resistant OCD patient. Thirty seven patients were randomly assigned to either active rTMS or to sham. Active rTMS with the frequency of 1 Hz at 110 % of motor threshold was administered over the left dorso-lateral prefrontal cortex. The same time schedule has been used for the sham administration. Thirty four patients finished the study, three patients dropped out at the beginning. Psychopathology was assessed by CGI, HAMA, Y-BOCS, and BAI by an indepen¬dent reviewer. Both groups improved but the treatment effect did not differ between them.
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