In Salmonella enterica, resistance to antibiotics can be caused by the presence of SGI1, transposons or conjugative plasmids. In this study we were interested in the relative contribution of these genetic elements to the antibiotic resistance of S. enterica isolates collected within a single year in the Czech Republic from animal sources. Altogether 123 antibiotic-resistant isolates belonging to 16 different S. enterica serovars were classified into 3 groups according to the presence of SGI1 and the presence of integrons. The first group consisted of 62 strains in which neither SGI1 nor class 1 integron was detected. A high diversity among serovars and resistance phenotypes was found in this group. The second group consisted of 56 strains positive for both the SGI1 and class 1 integron, out of which 55 belonged to serovar Typhimurium and one to a nonmotile serovar [4,12] which harboured the SGI1-B variant. The third group comprised five strains which were positive for class 1 integron but negative for the SGI1. Sequencing of the integrons in these isolates identified integron with sat1 and aadA1 gene cassettes in S. Sandiego and S. Pullorum, dfrA1 and aadA1 gene cassettes in S. Typhimurium integron, and aadA21 gene cassette in S. Braenderub and S. Zanzibar.

Veterinary Research Institute Hudcova 70 621 00 Brno Czech Republic

000      

03284naa 2200493 a 4500

001      

bmc11006168

003      

CZ-PrNML

005      

20121130101006.0

008      

110331s2009 ne e eng||

009      

AR

040    __

$a ABA008 $b cze $c ABA008 $d ABA008 $e AACR2

041    0_

$a eng

044    __

$a ne

100    1_

$a Havlíčková, Hana. $7 mzk2015895647

245    10

$a Distribution of integrons and SGI1 among antibiotic-resistant Salmonella enterica isolates of animal origin / $c H Havlickova, H Hradecka, I Bernardyova, I Rychlik

314    __

$a Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic.

520    9_

$a In Salmonella enterica, resistance to antibiotics can be caused by the presence of SGI1, transposons or conjugative plasmids. In this study we were interested in the relative contribution of these genetic elements to the antibiotic resistance of S. enterica isolates collected within a single year in the Czech Republic from animal sources. Altogether 123 antibiotic-resistant isolates belonging to 16 different S. enterica serovars were classified into 3 groups according to the presence of SGI1 and the presence of integrons. The first group consisted of 62 strains in which neither SGI1 nor class 1 integron was detected. A high diversity among serovars and resistance phenotypes was found in this group. The second group consisted of 56 strains positive for both the SGI1 and class 1 integron, out of which 55 belonged to serovar Typhimurium and one to a nonmotile serovar [4,12] which harboured the SGI1-B variant. The third group comprised five strains which were positive for class 1 integron but negative for the SGI1. Sequencing of the integrons in these isolates identified integron with sat1 and aadA1 gene cassettes in S. Sandiego and S. Pullorum, dfrA1 and aadA1 gene cassettes in S. Typhimurium integron, and aadA21 gene cassette in S. Braenderub and S. Zanzibar.

650    _2

$a zvířata $7 D000818

650    _2

$a antibakteriální látky $x farmakologie $7 D000900

650    _2

$a počet mikrobiálních kolonií $x veterinární $7 D015169

650    _2

$a DNA bakterií $x genetika $x chemie $7 D004269

650    _2

$a vztah mezi dávkou a účinkem léčiva $7 D004305

650    _2

$a bakteriální léková rezistence $x genetika $7 D024881

650    _2

$a mnohočetná bakteriální léková rezistence $7 D024901

650    _2

$a genomové ostrovy $x genetika $7 D044404

650    _2

$a integrony $x genetika $7 D032023

650    _2

$a mikrobiální testy citlivosti $x veterinární $7 D008826

650    _2

$a molekulární sekvence - údaje $7 D008969

650    _2

$a plazmidy $x genetika $7 D010957

650    _2

$a polymerázová řetězová reakce $x veterinární $7 D016133

650    _2

$a salmonelová infekce u zvířat $x farmakoterapie $x mikrobiologie $7 D012481

650    _2

$a Salmonella enterica $x genetika $x účinky léků $7 D019779

650    _2

$a Sequence Analysis, DNA

650    _2

$a Serotyping $x ve [Veterinary]

650    _2

$a financování organizované $7 D005381

651    _2

$a Česká republika $7 D018153

700    1_

$a Hradecká, Helena $7 xx0127553

700    1_

$a Bernardyová, I. $7 _AN062255

700    1_

$a Rychlík, Ivan, $d 1966- $7 xx0037983

773    0_

$t Veterinary Microbiology $w MED00005709 $g Roč. 133, č. 1-2 (2009), s. 193-198 $x 0378-1135

910    __

$a ABA008 $b x $y 2

990    __

$a 20110414100333 $b ABA008

991    __

$a 20121130101035 $b ABA008

999    __

$a ok $b bmc $g 833781 $s 698260

BAS    __

$a 3

BMC    __

$a 2009 $b 133 $c 1-2 $d 193-198 $i 0378-1135 $m Veterinary microbiology $n Vet Microbiol $x MED00005709

LZP    __

$a 2011-1B09/dkme