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Direct C-H borylation and C-H arylation of pyrrolo[2,3-d]pyrimidines: synthesis of 6,8-disubstituted 7-deazapurines
M. Klečka, R. Pohl, B. Klepetářová, M. Hocek
Jazyk angličtina Země Velká Británie
- MeSH
- financování organizované MeSH
- katalýza MeSH
- puriny chemická syntéza MeSH
- pyrimidiny chemie MeSH
- pyrroly chemie MeSH
- sloučeniny boru chemie MeSH
- tubercidin MeSH
Novel direct C-H borylations of 7-deazapurines to position 8 by B2pin2 under Ir catalysis were followed by Suzuki cross-couplings with aryl halides and other functional group transformations to give diverse 8-substituted 7-deazaadenines.
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- $a Direct C-H borylation and C-H arylation of pyrrolo[2,3-d]pyrimidines: synthesis of 6,8-disubstituted 7-deazapurines / $c M. Klečka, R. Pohl, B. Klepetářová, M. Hocek
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- $a Institute of Organic Chemistry and Biochemistry, v.v.i., Academy of Sciences of the Czech Republic, Gilead & IOCB Research Center, Flemingovo nam. 2, CZ-16610, Prague 6, Czech Republic.
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- $a Novel direct C-H borylations of 7-deazapurines to position 8 by B2pin2 under Ir catalysis were followed by Suzuki cross-couplings with aryl halides and other functional group transformations to give diverse 8-substituted 7-deazaadenines.
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