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Acyclic nucleoside phosphonates: An unfinished story
Erik De Clercq
Jazyk angličtina Země Česko Médium elektronický zdroj
NLK
ProQuest Central
od 2005-01-01 do 2011
- MeSH
- antivirové látky MeSH
- klinická chemie MeSH
- nukleosidy MeSH
- nukleotidy MeSH
- organofosfonáty MeSH
While cidofovir, adefovir and tenofovir are the three acyclic nucleoside phosphonates (ANPs) that have been licensed for clinical use (the latter as a single-, double- and triple-drug combination), there are many more ANPs that await their application for medical or veterinary use: (S)-HPMPA, (S)-HPMPDAP, cPrPMEDAP, (R)-HPMPO-DAPy, PMEO-DAPy, 5-X-PMEO-DAPy, (R)-PMPO-DAPy, (S)-HPMP-5-azaC, and cyclic (S)-HPMP-5-azaC, and alkoxyalkyl prodrugs thereof.
Acyclic nucleoside phosphonates: An unfinished story [elektronický zdroj] /
Literatura
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