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Interferon gamma receptor expression on granulocytes of cardiac surgical patients is modulated differently by the type of cardiopulmonary bypass used
K. Jankovicova, M. Kolackova, P. Kunes, Z. Holubcova, J. Krejsek, J. Mandak,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu srovnávací studie, časopisecké články
NLK
ProQuest Central
od 1997-01-01 do 2015-11-30
SAGE Publications Journals
od 1999-01-01 do 2015-12-31
CINAHL Plus with Full Text (EBSCOhost)
od 1997-01-01 do 2016-05-31
Medline Complete (EBSCOhost)
od 1997-01-01 do 2016-05-31
Nursing & Allied Health Database (ProQuest)
od 1997-01-01 do 2015-11-30
Health & Medicine (ProQuest)
od 1997-01-01 do 2015-11-30
SAGE Journals
od 2012-01-01 do 2012-05-31
PubMed
21983125
DOI
10.1177/0267659111424635
Knihovny.cz E-zdroje
- MeSH
- granulocyty metabolismus MeSH
- kardiochirurgické výkony MeSH
- kardiopulmonální bypass klasifikace metody MeSH
- lidé středního věku MeSH
- lidé MeSH
- miniaturizace MeSH
- monocyty metabolismus MeSH
- pooperační období MeSH
- průtoková cytometrie MeSH
- receptory interferonů metabolismus MeSH
- senioři MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
Aims: To follow the IFNγ receptor expression on monocytes and granulocytes of cardiac surgical patients with respect to the type of cardiopulmonary bypass (CPB). Methods: Expression of IFNγ receptor on monocytes and granulocytes of 26 cardiac surgical patients operated with the use of either "standard" or "miniaturised" CPB was determined by flow cytometry. Results: The significant increase in IFNγ receptor expression on monocytes on the 1(st) and on the 3(rd) postoperative days was revealed in both groups of patients (p<0.001) irrespective of the type of CPB used, being non-significantly different between groups. In contrast, the expression of IFNγ on granulocytes displayed significant differences in terms of the CPB used. Whereas, in "standard" CPB patients, granulocyte INFγ receptor expression reached its maximum immediately after surgery (p<0.01), in "miniivasive" CPB patients, the peak in INFγ receptor expression was postponed to the 1(st) postoperative day (p<0.05). Statistically significantly higher IFNγ receptor expression on granulocytes was found in "standard" CPB patients (p<0.05). Conclusion: Compared to "miniaturised" CPB patients, the significantly higher IFNγ receptor expression on granulocytes was found in "standard" CPB patients (p<0.05) on the 1(st) postoperative day.
Citace poskytuje Crossref.org
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