• Something wrong with this record ?

No effect of physiotherapy on the serum levels of adipocytokines in patients with ankylosing spondylitis

H. Hulejová, A. Levitová, M. Kuklová, J. Štochl, M. Haluzík, K. Pavelka, J. Vencovský, L. Šenolt

. 2012 ; 31 (1) : 67-71.

Language English Country Germany

Document type Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't

Persistent link   https://www.medvik.cz/link/bmc12024438
E-resources Online Full text

NLK ProQuest Central from 1997-01-01 to 1 year ago
Medline Complete (EBSCOhost) from 2000-01-01 to 1 year ago
Health & Medicine (ProQuest) from 1997-01-01 to 1 year ago

Links

PubMed 21618078
DOI 10.1007/s10067-011-1773-7
Knihovny.cz E-resources

To investigate the effect of intensive physiotherapy on disease activity and serum levels of adipocytokines in patients with ankylosing spondylitis (AS). Twenty-six patients with AS were included in this study. Intensive physiotherapy was performed twice a week for a period of 3 months. The Bath AS Disease Activity Index (BASDAI) and the Bath AS Functional Index (BASFI) were assessed at inclusion and after 3 months. Leptin, adiponectin, resistin and visfatin serum levels were analysed by ELISA assays. Patients had mild to moderate disease activity. Baseline levels of adipocytokines did not correlate with indicators of disease activity, functional status or acute-phase reactants. After the 3 months of intensive physiotherapy, BASDAI significantly decreased from 2.98 to 1.8 (p = 0.01) and BASFI improved from 2.31 to 1.37 (p = 0.05), while there were no changes in serum levels of CRP, ESR and adipocytokines. In addition, baseline levels of adipocytokines did not predict the change of disease activity or functional ability. Intensive physiotherapy effectively reduces all clinical measures of disease activity, but it is not associated with a significant change in acute-phase reactants or serum levels of adipocytokines.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc12024438
003      
CZ-PrNML
005      
20160215091932.0
007      
ta
008      
120815s2012 gw f 000 0#eng||
009      
AR
024    7_
$a 10.1007/s10067-011-1773-7 $2 doi
035    __
$a (PubMed)21618078
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a gw
100    1_
$a Hulejová, Hana $u Institute of Rheumatology, Department of Experimental and Clinical Rheumatology, Prague, Czech Republic; Institute of Rheumatology, Experimental Connective Tissue Research Laboratory, Prague, Czech Republic $7 xx0077461
245    10
$a No effect of physiotherapy on the serum levels of adipocytokines in patients with ankylosing spondylitis / $c H. Hulejová, A. Levitová, M. Kuklová, J. Štochl, M. Haluzík, K. Pavelka, J. Vencovský, L. Šenolt
520    9_
$a To investigate the effect of intensive physiotherapy on disease activity and serum levels of adipocytokines in patients with ankylosing spondylitis (AS). Twenty-six patients with AS were included in this study. Intensive physiotherapy was performed twice a week for a period of 3 months. The Bath AS Disease Activity Index (BASDAI) and the Bath AS Functional Index (BASFI) were assessed at inclusion and after 3 months. Leptin, adiponectin, resistin and visfatin serum levels were analysed by ELISA assays. Patients had mild to moderate disease activity. Baseline levels of adipocytokines did not correlate with indicators of disease activity, functional status or acute-phase reactants. After the 3 months of intensive physiotherapy, BASDAI significantly decreased from 2.98 to 1.8 (p = 0.01) and BASFI improved from 2.31 to 1.37 (p = 0.05), while there were no changes in serum levels of CRP, ESR and adipocytokines. In addition, baseline levels of adipocytokines did not predict the change of disease activity or functional ability. Intensive physiotherapy effectively reduces all clinical measures of disease activity, but it is not associated with a significant change in acute-phase reactants or serum levels of adipocytokines.
650    _2
$a adipokiny $x krev $7 D054392
650    _2
$a dospělí $7 D000328
650    _2
$a terapie cvičením $x metody $7 D005081
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a zdravotní stav $7 D006304
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé středního věku $7 D008875
650    _2
$a stupeň závažnosti nemoci $7 D012720
650    _2
$a ankylózující spondylitida $x krev $x patofyziologie $x terapie $7 D013167
650    _2
$a výsledek terapie $7 D016896
650    _2
$a mladý dospělý $7 D055815
655    _2
$a klinické zkoušky $7 D016430
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Levitová, Andrea $7 kv2012707374 $u Department of Sports Medicine and Adapted Physical Education, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic
700    1_
$a Kuklová, M. $d 1983- $4 aut $7 _AN069300 $u Institute of Rheumatology, Department of Experimental and Clinical Rheumatology, Prague, Czech Republic
700    1_
$a Štochl, Jan, $d 1978- $7 jx20090130018 $u Department of Kinanthropology, Charles University, Prague, Czech Republic
700    1_
$a Haluzík, Martin, $d 1970- $7 xx0000707 $u Third Department of Medicine, First Faculty of Medicine, Charles University, Prague, Czech Republic
700    1_
$a Pavelka, Karel, $d 1954- $7 jn99240000847 $u Institute of Rheumatology, Department of Experimental and Clinical Rheumatology, Prague, Czech Republic
700    1_
$a Vencovský, Jiří, $d 1953- $7 jo20000080529 $u Institute of Rheumatology, Department of Experimental and Clinical Rheumatology, Prague, Czech Republic
700    1_
$a Šenolt, Ladislav, $d 1976- $7 xx0056558 $u Institute of Rheumatology, Department of Experimental and Clinical Rheumatology, Prague, Czech Republic
773    0_
$w MED00001162 $t Clinical rheumatology $x 1434-9949 $g Roč. 31, č. 1 (2012), s. 67-71
856    41
$u https://pubmed.ncbi.nlm.nih.gov/21618078 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y m $z 0
990    __
$a 20120815 $b ABA008
991    __
$a 20160215092117 $b ABA008
999    __
$a ok $b bmc $g 946586 $s 781766
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2012 $b 31 $c 1 $d 67-71 $i 1434-9949 $m Clinical rheumatology $n Clin Rheumatol $x MED00001162
LZP    __
$b NLK118 $a Pubmed-20120815/12/02

Find record

Citation metrics

Archiving options