• Something wrong with this record ?

Sensitization, epileptic-like symptoms and local synchronization in patients with paranoid schizophrenia

P. Bob, M. Palus, M. Susta, K. Glaslova

. 2010 ; 34 (1) : 143-146.

Language English Country England, Great Britain

Document type Journal Article, Research Support, Non-U.S. Gov't

Recent findings indicate that changes in synchronization of neural activities underlying sensitization and kindling could be more comprehensively understood using nonlinear methods. With this aim we have examined local synchronization using novel measure of coarse-grained information rate (CIR) in 8 EEG signals recorded at different cortical areas in 44 patients with paranoid schizophrenia. The values of local synchronization that could reflect sensitization related changes in EEG activities of cortical sites were then related to psychometric measures of epileptic-like symptoms and positive and negative schizophrenia symptoms (PANSS). While no significant correlations between CIR and positive and negative symptoms have been found, statistically significant relationships described by Spearman correlation coefficients between CIR indices and results of LSCL-33 have been observed in 7 (of 8) EEG channels (r in the range from 0.307 to 0.374, p<0.05). Results of this study provide first supportive evidence for the relationship between local synchronization measured by CIR and epileptic-like symptoms in schizophrenia.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc12025492
003      
CZ-PrNML
005      
20130126192359.0
007      
ta
008      
120816s2010 enk f 000 0#eng||
009      
AR
024    7_
$a 10.1016/j.pnpbp.2009.10.015 $2 doi
035    __
$a (PubMed)19878702
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Bob, Petr $7 uk2005277741 $u Center for Neuropsychiatric Research of Traumatic Stress, First Faculty of Medicine, Charles University, Prague, Czech Republic. petrbob@netscape.net
245    10
$a Sensitization, epileptic-like symptoms and local synchronization in patients with paranoid schizophrenia / $c P. Bob, M. Palus, M. Susta, K. Glaslova
520    9_
$a Recent findings indicate that changes in synchronization of neural activities underlying sensitization and kindling could be more comprehensively understood using nonlinear methods. With this aim we have examined local synchronization using novel measure of coarse-grained information rate (CIR) in 8 EEG signals recorded at different cortical areas in 44 patients with paranoid schizophrenia. The values of local synchronization that could reflect sensitization related changes in EEG activities of cortical sites were then related to psychometric measures of epileptic-like symptoms and positive and negative schizophrenia symptoms (PANSS). While no significant correlations between CIR and positive and negative symptoms have been found, statistically significant relationships described by Spearman correlation coefficients between CIR indices and results of LSCL-33 have been observed in 7 (of 8) EEG channels (r in the range from 0.307 to 0.374, p<0.05). Results of this study provide first supportive evidence for the relationship between local synchronization measured by CIR and epileptic-like symptoms in schizophrenia.
650    _2
$a dospělí $7 D000328
650    _2
$a korová synchronizace $7 D003344
650    _2
$a elektroencefalografie $x metody $7 D004569
650    _2
$a epilepsie $x etiologie $7 D004827
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a paranoidní schizofrenie $x komplikace $7 D012563
650    _2
$a mladý dospělý $7 D055815
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Paluš, Milan, $d 1963- $7 xx0089955
700    1_
$a Šusta, Marek $7 jn20001227496
700    1_
$a Gláslová, Kateřina, $d 1972- $7 xx0107558
773    0_
$w MED00003930 $t Progress in neuro-psychopharmacology & biological psychiatry $x 1878-4216 $g Roč. 34, č. 1 (2010), s. 143-146
856    41
$u https://pubmed.ncbi.nlm.nih.gov/19878702 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y m
990    __
$a 20120816 $b ABA008
991    __
$a 20130126192542 $b ABA008
999    __
$a ok $b bmc $g 947534 $s 782838
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2010 $b 34 $c 1 $d 143-146 $i 1878-4216 $m Progress in neuro-psychopharmacology & biological psychiatry $n Prog Neuropsychopharmacol Biol Psychiatry $x MED00003930
LZP    __
$a Pubmed-20120816/10/02

Find record

Citation metrics

Loading data ...

Archiving options

Loading data ...