-
Je něco špatně v tomto záznamu ?
High-performance analysis of biological systems dynamics with the DiVinE model checker
J. Barnat, L. Brim, D. Safránek,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, práce podpořená grantem
NLK
Free Medical Journals
od 2000 do Před 2 roky
PubMed Central
od 2008
Medline Complete (EBSCOhost)
od 2000-01-01 do Před 1 rokem
Oxford Journals Open Access Collection
od 2000
ROAD: Directory of Open Access Scholarly Resources
od 2000
PubMed
20478855
DOI
10.1093/bib/bbp074
Knihovny.cz E-zdroje
- MeSH
- algoritmy MeSH
- biologické modely MeSH
- biologie metody MeSH
- navrhování softwaru MeSH
- počítačová simulace MeSH
- programovací jazyk MeSH
- software MeSH
- systémová integrace MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
The current interest in systems biology is to gain a better understanding of how the complex dynamic behaviour of the cell emerges from mutual interactions of molecular species. When solving such a nontrivial goal, biological data have to be necessarily integrated with mathematical modelling and computer analysis. Since the key aspect of biological modelling is based on unifying several kinds of data captured in terms of large-scale biological networks, scalable and automatized methods are necessary to obtain novel predictions and understanding. In this review, we provide a brief description of the tool DiVinE adapted for automatized analysis of biological systems dynamics. The tool employs high-performance computing techniques to enable analysis of large models.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc12025712
- 003
- CZ-PrNML
- 005
- 20121206122814.0
- 007
- ta
- 008
- 120817e20100428enk f 000 0#eng||
- 009
- AR
- 024 7_
- $a 10.1093/bib/bbp074 $2 doi
- 035 __
- $a (PubMed)20478855
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a Barnat, Jirí $u Masaryk University, Botanická 68a, 602 00 Brno, Czech Republic.
- 245 10
- $a High-performance analysis of biological systems dynamics with the DiVinE model checker / $c J. Barnat, L. Brim, D. Safránek,
- 520 9_
- $a The current interest in systems biology is to gain a better understanding of how the complex dynamic behaviour of the cell emerges from mutual interactions of molecular species. When solving such a nontrivial goal, biological data have to be necessarily integrated with mathematical modelling and computer analysis. Since the key aspect of biological modelling is based on unifying several kinds of data captured in terms of large-scale biological networks, scalable and automatized methods are necessary to obtain novel predictions and understanding. In this review, we provide a brief description of the tool DiVinE adapted for automatized analysis of biological systems dynamics. The tool employs high-performance computing techniques to enable analysis of large models.
- 650 _2
- $a algoritmy $7 D000465
- 650 _2
- $a biologie $x metody $7 D001695
- 650 _2
- $a počítačová simulace $7 D003198
- 650 _2
- $a biologické modely $7 D008954
- 650 _2
- $a programovací jazyk $7 D011381
- 650 _2
- $a software $7 D012984
- 650 _2
- $a navrhování softwaru $7 D012985
- 650 _2
- $a systémová integrace $7 D018511
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Brim, Lubos
- 700 1_
- $a Safránek, Dravid
- 773 0_
- $w MED00006943 $t Briefings in bioinformatics $x 1477-4054 $g Roč. 11, č. 3 (20100428), s. 301-12
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/20478855 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y m
- 990 __
- $a 20120817 $b ABA008
- 991 __
- $a 20121206122848 $b ABA008
- 999 __
- $a ok $b bmc $g 947754 $s 783058
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2010 $b 11 $c 3 $d 301-12 $e 20100428 $i 1477-4054 $m Briefings in bioinformatics $n Brief Bioinform $x MED00006943
- LZP __
- $a Pubmed-20120817/10/03