• Je něco špatně v tomto záznamu ?

Effect of stimulation on the input parameters of stochastic leaky integrate-and-fire neuronal model

P. Lansky, P. Sanda, J. He,

. 2009 ; 104 (3-4) : 160-6. [pub] 20091126

Jazyk angličtina Země Francie

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc12025993

The Ornstein-Uhlenbeck neuronal model is specified by two types of parameters. One type corresponds to the properties of the neuronal membrane, whereas the second type (local average rate of the membrane depolarization and its variability) corresponds to the input of the neuron. In this article, we estimate the parameters of the second type from an intracellular record during neuronal firing caused by stimulation (audio signal). We compare the obtained estimates with those from the spontaneous part of the record. As predicted from the model construction, the values of the input parameters are larger for the periods when neuron is stimulated than for the spontaneous ones. Finally, the firing regimen of the model is checked. It is confirmed that the neuron is in the suprathreshold regimen during the stimulation.

000      
00000naa a2200000 a 4500
001      
bmc12025993
003      
CZ-PrNML
005      
20121207121446.0
007      
ta
008      
120817e20091126fr f 000 0#eng||
009      
AR
024    7_
$a 10.1016/j.jphysparis.2009.11.019 $2 doi
035    __
$a (PubMed)19944155
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a fr
100    1_
$a Lansky, Petr $u Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic. lansky@biomed.cas.cz
245    10
$a Effect of stimulation on the input parameters of stochastic leaky integrate-and-fire neuronal model / $c P. Lansky, P. Sanda, J. He,
520    9_
$a The Ornstein-Uhlenbeck neuronal model is specified by two types of parameters. One type corresponds to the properties of the neuronal membrane, whereas the second type (local average rate of the membrane depolarization and its variability) corresponds to the input of the neuron. In this article, we estimate the parameters of the second type from an intracellular record during neuronal firing caused by stimulation (audio signal). We compare the obtained estimates with those from the spontaneous part of the record. As predicted from the model construction, the values of the input parameters are larger for the periods when neuron is stimulated than for the spontaneous ones. Finally, the firing regimen of the model is checked. It is confirmed that the neuron is in the suprathreshold regimen during the stimulation.
650    _2
$a akustická stimulace $x metody $7 D000161
650    _2
$a akční potenciály $x fyziologie $7 D000200
650    _2
$a zvířata $7 D000818
650    _2
$a elektroencefalografie $7 D004569
650    _2
$a morčata $7 D006168
650    _2
$a membránové potenciály $x fyziologie $7 D008564
650    _2
$a modely neurologické $7 D008959
650    _2
$a nervové dráhy $x fyziologie $7 D009434
650    _2
$a neurony $x klasifikace $x fyziologie $7 D009474
650    _2
$a reakční čas $x fyziologie $7 D011930
650    _2
$a počítačové zpracování signálu $7 D012815
650    _2
$a stochastické procesy $7 D013269
650    _2
$a časové faktory $7 D013997
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Sanda, Pavel
700    1_
$a He, Jufang
773    0_
$w MED00008628 $t Journal of physiology, Paris $x 1769-7115 $g Roč. 104, č. 3-4 (20091126), s. 160-6
856    41
$u https://pubmed.ncbi.nlm.nih.gov/19944155 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y m
990    __
$a 20120817 $b ABA008
991    __
$a 20121207121520 $b ABA008
999    __
$a ok $b bmc $g 948035 $s 783339
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2009 $b 104 $c 3-4 $d 160-6 $e 20091126 $i 1769-7115 $m Journal of physiology (Paris) $n J Physiol Paris $x MED00008628
LZP    __
$a Pubmed-20120817/10/03

Najít záznam

Citační ukazatele

Možnosti archivace