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Parental education and lung function of children in the PATY study

H. Slachtova, U. Gehring, G. Hoek, H. Tomaskova, H. Luttmann-Gibson, H. Moshammer, A. Paldy, S. Pattenden, K. Slotova, F. Speizer, R. Zlotkowska, J. Heinrich

. 2011 ; 26 (1) : 45-54.

Jazyk angličtina Země Nizozemsko

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc12027343
E-zdroje Online Plný text

NLK ProQuest Central od 1997-01-01 do 2017-12-31
Medline Complete (EBSCOhost) od 2005-01-01 do Před 1 rokem
Health & Medicine (ProQuest) od 1997-01-01 do 2017-12-31
Health Management Database (ProQuest) od 1997-01-01 do 2017-12-31
Public Health Database (ProQuest) od 1997-01-01 do 2017-12-31

Studies of the relationships between low socio-economic status and impaired lung function were conducted mainly in Western European countries and North America. East-West differences remain unexplored. Associations between parental education and lung function were explored using data on 24,010 school-children from eight cross-sectional studies conducted in North America, Western and Eastern Europe. Parental education was defined as low and high using country-specific classifications. Country-specific estimates of effects of low parental education on volume and flow parameters were obtained using linear and logistic regression, controlling for early life and other individual risk factors. Meta-regressions were used for assessment of heterogeneity between country-specific estimates. The association between low parental education and lung function was not consistent across the countries, but showed a more pronounced inverse gradient in the Western countries. The most consistent decrease associated with low parental education was found for peak expiratory flow (PEF), ranging from -2.80 to -1.14%, with statistically significant associations in five out of eight countries. The mean odds ratio for low PEF (<75% of predicted) was 1.34 (95% CI 1.06-1.70) after all adjustments. Although social gradients were attenuated after adjusting for known risk factors, these risk factors could not completely explain the social gradient in lung function.

Citace poskytuje Crossref.org

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