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A proteomic view of the host-pathogen interaction: The host perspective
A. Hartlova, Z. Krocova, L. Cerveny, J. Stulik,
Jazyk angličtina Země Německo
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
PubMed
21726044
DOI
10.1002/pmic.201000767
Knihovny.cz E-zdroje
- MeSH
- bakteriální infekce imunologie metabolismus MeSH
- interakce hostitele a patogenu MeSH
- lidé MeSH
- proteiny analýza MeSH
- proteom imunologie metabolismus MeSH
- proteomika metody MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
The host-pathogen interaction represents a complex and dynamic biological system. The outcome of this interaction is dependent on the microbial pathogen properties to establish infection and the ability of the host to control infection. Although bacterial pathogens have evolved a variety of strategies to subvert host defense functions, several general mechanisms have been shown to be shared among these pathogens. As a result, host effectors that are critical for pathogen entry, survival and replication inside the host cells have become a new paradigm for antimicrobial targeting. This review focuses on the potential utility of a proteomics approach in defining the host-pathogen interaction from the host's perspective.
Citace poskytuje Crossref.org
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