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Apoptosis and expression of Bcl-2 in human endometrium in natural and artificial cycles
P. Havelka, I. Oborná, J. Brezinová, V. Lichnovský
Jazyk angličtina Země Česko
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- apoptóza účinky léků MeSH
- endometrium cytologie metabolismus MeSH
- estradiol analogy a deriváty farmakologie MeSH
- konjugované estrogeny (USP) farmakologie MeSH
- lidé MeSH
- luteální fáze MeSH
- menstruační cyklus účinky léků MeSH
- protoonkogenní proteiny c-bcl-2 metabolismus MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Apoptosis plays a significant role in differentiation of many organs and helps to maintain homeostasis. The occurrence of apoptosis (using the apoptotic index) and expression of regulation protein Bcl-2 in the human endometrium was evaluated within the secretory phase of both the natural cycle, and an artificial one. Oral hormonal substitution used in this design induced similar, but more marked dynamic changes in Bcl-2 expression in the mid-secretory endometrium as were observed in the natural cycle, primarily in the surface and glandular epithelium of the endometrium. The apoptosis revealed similar a trend, but not significantly different.
Department of Obstetrics and Gynaecology University Hospital Olomouc
Institute of Histology and Embryology Palacky University Olomouc
Citace poskytuje Crossref.org
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