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An embolus in the right atrium caught in the Chiari network and resistant to thrombolysis
M. Zuzana, W. Petr, B. Dana, P. Martin, L. Hana, K. Dana, K. Miroslav, K. Ludmila, K. Jan,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu kazuistiky, časopisecké články, audiovizuální média
NLK
PubMed Central
od 2008
Europe PubMed Central
od 2008 do Před 2 roky
ProQuest Central
od 2008-01-01 do Před 1 měsícem
Nursing & Allied Health Database (ProQuest)
od 2008-01-01 do Před 1 měsícem
Health & Medicine (ProQuest)
od 2008-01-01 do Před 1 měsícem
PubMed
22791494
DOI
10.1136/bcr.09.2008.1019
Knihovny.cz E-zdroje
- MeSH
- dospělí MeSH
- fibrinolytika terapeutické užití MeSH
- heparin terapeutické užití MeSH
- kardiopulmonální bypass MeSH
- kombinovaná terapie MeSH
- lidé MeSH
- srdeční síně abnormality patologie MeSH
- tromboembolie diagnóza farmakoterapie etiologie chirurgie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- audiovizuální média MeSH
- časopisecké články MeSH
- kazuistiky MeSH
This case report describes a patient with thromboemboli trapped in the Chiari network within the right side of the heart and resistant to thrombolysis. The right atrial masses were completely removed under cardiopulmonary bypass. Histological evaluation confirmed a mixed thromboemboli, with thrombus structures showing signs of organisation and surrounded by a fibrous capsule. The plasma level of the plasminogen activator inhibitor type-1 (PAI-1) was 50% higher than the normal upper limit. In this presented case, the Chiari network displayed a protective function but the expansion and organisation of the thromboembolus found there made it resistant to lytic treatment. Another important factor that could have influenced the resistance to thrombolysis was the high level of PAI-1.
Citace poskytuje Crossref.org
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- $a This case report describes a patient with thromboemboli trapped in the Chiari network within the right side of the heart and resistant to thrombolysis. The right atrial masses were completely removed under cardiopulmonary bypass. Histological evaluation confirmed a mixed thromboemboli, with thrombus structures showing signs of organisation and surrounded by a fibrous capsule. The plasma level of the plasminogen activator inhibitor type-1 (PAI-1) was 50% higher than the normal upper limit. In this presented case, the Chiari network displayed a protective function but the expansion and organisation of the thromboembolus found there made it resistant to lytic treatment. Another important factor that could have influenced the resistance to thrombolysis was the high level of PAI-1.
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