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Biomechanical characterization of cartilages by a novel approach of blunt impact testing
F. Varga, M. Drzík, M. Handl, J. Chlpík, P. Kos, E. Filová, M. Rampichová, A. Necas, T. Trc, E. Amler
Language English Country Czech Republic
Document type Journal Article, Research Support, Non-U.S. Gov't
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- MeSH
- Models, Biological MeSH
- Time Factors MeSH
- Chondrocytes physiology MeSH
- Cartilage, Articular physiology MeSH
- Cells, Cultured MeSH
- Humans MeSH
- Stress, Mechanical MeSH
- Compressive Strength MeSH
- Elasticity MeSH
- Prosthesis Failure MeSH
- Materials Testing * MeSH
- Tissue Engineering * MeSH
- Tissue Scaffolds * MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
The present article introduces a novel method of characterizing the macromechanical cartilage properties based on dynamic testing. The proposed approach of instrumented impact testing shows the possibility of more detailed investigation of the acting dynamic forces and corresponding deformations within the wide range of strain rates and loads, including the unloading part of stress-strain curves and hysteresis loops. The presented results of the unconfined compression testing of both the native joint cartilage tissues and potential substitute materials outlined the opportunity to measure the dissipation energy and thus to identify the initial mechanical deterioration symptoms and to introduce a better definition of material damage. Based on the analysis of measured specimen deformation, the intact and pathologically changed cartilage tissue can be distinguished and the differences revealed.
Department of Biophysics 2nd Faculty of Medicine Charles University Prague Czech Republic
Institute of Experimental Medicine Academy of Sciences of the Czech Republic Prague Czech Republic
International Laser Centre Bratislava Slovakia
Orthopedic Clinic 2nd Faculty of Medicine Charles University Prague Czech Republic
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