Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Ultravysokomolekulární polyethylen pro kloubní náhrady se zvýšenou životností
[Ultrahigh molecular weight polyethylene for total joint replacements with longer lifetime]

Miroslav Šlouf, Taťana Vacková, Martina Nevoralová, Jana Mikešová, Jiří Dybal, Jan Pilař, Alexander Zhigunov, Jiří Kotek, Jana Kredatusová, Petr Fulín

. 2013 ; 107 (10) : 783-790.

Language Czech Country Czech Republic

Persistent link   https://www.medvik.cz/link/bmc14040098

Grant support
NT12229 MZ0 CEP Register

Ultrahigh molecular weight polyethylene (UHMWPE) is a key component of modern total joint replacements (TJR). The most frequently replaced human joints are hips and knees, followed by shoulders, elbows, etc. However, UHMWPE liners are the most loaded components of the implants. Consequently, the main materialrelated reasons of TJR failures are wear and oxidative degradation of the polymer. Resistance to wear (i.e. release of microscopic particles from the polymer surface) is increased by radiation-induced crosslinking. Oxidation stability (i.e. resistance of polymer to chain scissions and deterioration of mechanical properties) is enhanced by means of suitable thermal treatment and sterilization protocols. The most recent trend is to employ a biocompatible stabilizer – vitamin E – for further improvement and finetuning of UHMWPE performance. This review summarizes the recent developments in UHMWPE modifications, which come both from the author’s institute and from the world, and which should further increase lifespan of total joint replacements.

Ultrahigh molecular weight polyethylene for total joint replacements with longer lifetime

Bibliography, etc.

Literatura

000      
00000naa a2200000 a 4500
001      
bmc14040098
003      
CZ-PrNML
005      
20240117103753.0
007      
ta
008      
140103s2013 xr f 000 0cze||
009      
AR
040    __
$a ABA008 $d ABA008 $e AACR2 $b cze
041    0_
$a cze $b eng
044    __
$a xr
100    1_
$a Šlouf, Miroslav, $d 1973- $7 xx0107048 $u Ústav makromolekulární chemie AV ČR, v.v.i., Praha 6
245    10
$a Ultravysokomolekulární polyethylen pro kloubní náhrady se zvýšenou životností / $c Miroslav Šlouf, Taťana Vacková, Martina Nevoralová, Jana Mikešová, Jiří Dybal, Jan Pilař, Alexander Zhigunov, Jiří Kotek, Jana Kredatusová, Petr Fulín
246    31
$a Ultrahigh molecular weight polyethylene for total joint replacements with longer lifetime
504    __
$a Literatura
520    3_
$a Ultrahigh molecular weight polyethylene (UHMWPE) is a key component of modern total joint replacements (TJR). The most frequently replaced human joints are hips and knees, followed by shoulders, elbows, etc. However, UHMWPE liners are the most loaded components of the implants. Consequently, the main materialrelated reasons of TJR failures are wear and oxidative degradation of the polymer. Resistance to wear (i.e. release of microscopic particles from the polymer surface) is increased by radiation-induced crosslinking. Oxidation stability (i.e. resistance of polymer to chain scissions and deterioration of mechanical properties) is enhanced by means of suitable thermal treatment and sterilization protocols. The most recent trend is to employ a biocompatible stabilizer – vitamin E – for further improvement and finetuning of UHMWPE performance. This review summarizes the recent developments in UHMWPE modifications, which come both from the author’s institute and from the world, and which should further increase lifespan of total joint replacements.
650    12
$a artroplastiky kloubů $7 D019643
650    _2
$a protézy kloubů $7 D007595
650    12
$a polyethyleny $x chemická syntéza $x chemie $x terapeutické užití $7 D011095
650    _2
$a biokompatibilní materiály $x chemická syntéza $x chemie $x terapeutické užití $7 D001672
650    _2
$a testování materiálů $7 D008422
650    _2
$a biomechanika $7 D001696
650    _2
$a dávka záření $7 D011829
650    _2
$a alfa-tokoferol $7 D024502
650    _2
$a záření gama $7 D005720
650    12
$a polymery $x chemická syntéza $x chemie $x terapeutické užití $7 D011108
650    _2
$a lidé $7 D006801
700    1_
$a Vacková, Taťana $7 _AN076109 $u Ústav makromolekulární chemie AV ČR, v.v.i., Praha 6
700    1_
$a Nevoralová, Martina $u Ústav makromolekulární chemie AV ČR, v.v.i., Praha 6 $7 ntka173525
700    1_
$a Mikešová, Jana $u Ústav makromolekulární chemie AV ČR, v.v.i., Praha 6 $7 _AN076111
700    1_
$a Dybal, Jiří $7 xx0312810 $u Ústav makromolekulární chemie AV ČR, v.v.i., Praha 6
700    1_
$a Pilař, Jan $u Ústav makromolekulární chemie AV ČR, v.v.i., Praha 6 $7 _AN076112
700    1_
$a Zhigunov, Alexander $u Ústav makromolekulární chemie AV ČR, v.v.i., Praha 6 $7 xx0309192
700    1_
$a Kotek, Jiří $7 ntka173005 $u Ústav makromolekulární chemie AV ČR, v.v.i., Praha 6
700    1_
$a Kredatusová, Jana $u Ústav makromolekulární chemie AV ČR, v.v.i., Praha 6 $7 xx0240837
700    1_
$a Fulín, Petr $7 xx0231618 $u 1. Ortopedická klinika 1. LF UK a FN Motol, Praha
773    0_
$t Chemické listy $x 0009-2770 $g Roč. 107, č. 10 (2013), s. 783-790 $w MED00011010
856    41
$u http://www.chemicke-listy.cz/docs/full/2013_10_783-790.pdf $y plný text volně přístupný
910    __
$a ABA008 $b B 1918 $c 395 $z 0 $y 4
990    __
$a 20131230143704 $b ABA008
991    __
$a 20240117103749 $b ABA008
999    __
$a ok $b bmc $g 1004495 $s 838601
BAS    __
$a 3
BMC    __
$a 2013 $b 107 $c 10 $d 783-790 $i 0009-2770 $m Chemické listy $n Chem. Listy $x MED00011010
GRA    __
$a NT12229 $p MZ0
LZP    __
$c NLK137 $d 20140115 $a NLK 2013-20/mk
Back

Find record

Citation metrics

Archiving options