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Changes in cyclosporine A kinetics after experimental reduction of renal parenchyma
O. Schück, M. Bohdanecká, J. Šedivý, M. Krajíčková, M. Chadimová, K. Matoušovic
Jazyk angličtina Země Švýcarsko
Typ dokumentu práce podpořená grantem
Grantová podpora
IZ3094
MZ0
CEP - Centrální evidence projektů
PubMed
9358200
DOI
10.1007/bf03189808
Knihovny.cz E-zdroje
- MeSH
- časové faktory MeSH
- cyklosporin farmakokinetika krev MeSH
- imunosupresiva farmakokinetika krev MeSH
- krysa rodu rattus MeSH
- ledviny * metabolismus MeSH
- nefrektomie * metody MeSH
- renální insuficience metabolismus MeSH
- zvířata MeSH
- Check Tag
- krysa rodu rattus MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- práce podpořená grantem MeSH
Experimental chronic renal insufficiency (produced by 5/6 ablation of renal parenchyma) is associated with changes in the kinetics of oral (intragastric) cyclosporine A (CyA). Compared with animals with intact renal parenchyma, significantly lower levels of CyA are reached under these conditions. The factors responsible for reduced CyA availability under these conditions have not yet been identified.
Citace poskytuje Crossref.org
Literatura
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