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Serotonin (5-HT) correlates with adiponectin in overweight patients
Claus Muss, Thomas Endler
Language English Country Czech Republic
- MeSH
- Adiponectin * blood metabolism MeSH
- Insulin secretion MeSH
- Humans MeSH
- Metabolic Syndrome metabolism MeSH
- Obesity * metabolism MeSH
- Serotonin * metabolism urine secretion MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Female MeSH
We examined the relationship of two neurohormones with neuroendocrine impact (serotonin /5-HT/ and adiponectin) under standardized clinical conditions in an overweight cohort. Adiponectin was measured in serum and Serotonin was determined in the second morning urine samples. Serotonin correlated positively with adiponectin in our investigation Srho (+0.303; p=0.03). As high adiponectin level corresponds with a low risk of Insulin resistance our findings refer to possible improvement of prediabetic conditions in overweight patients tracking peripheral serotonin circulation. Further clinical evidence is mandatory to verify the effects of 5-HT in patients with metabolic syndrome
Literatura
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- $a We examined the relationship of two neurohormones with neuroendocrine impact (serotonin /5-HT/ and adiponectin) under standardized clinical conditions in an overweight cohort. Adiponectin was measured in serum and Serotonin was determined in the second morning urine samples. Serotonin correlated positively with adiponectin in our investigation Srho (+0.303; p=0.03). As high adiponectin level corresponds with a low risk of Insulin resistance our findings refer to possible improvement of prediabetic conditions in overweight patients tracking peripheral serotonin circulation. Further clinical evidence is mandatory to verify the effects of 5-HT in patients with metabolic syndrome
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