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Serotonin (5-HT) correlates with adiponectin in overweight patients
Claus Muss, Thomas Endler
Jazyk angličtina Země Česko
- MeSH
- adiponektin * krev metabolismus MeSH
- inzulin sekrece MeSH
- lidé MeSH
- metabolický syndrom metabolismus MeSH
- obezita * metabolismus MeSH
- serotonin * metabolismus moč sekrece MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
We examined the relationship of two neurohormones with neuroendocrine impact (serotonin /5-HT/ and adiponectin) under standardized clinical conditions in an overweight cohort. Adiponectin was measured in serum and Serotonin was determined in the second morning urine samples. Serotonin correlated positively with adiponectin in our investigation Srho (+0.303; p=0.03). As high adiponectin level corresponds with a low risk of Insulin resistance our findings refer to possible improvement of prediabetic conditions in overweight patients tracking peripheral serotonin circulation. Further clinical evidence is mandatory to verify the effects of 5-HT in patients with metabolic syndrome
Literatura
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- $a We examined the relationship of two neurohormones with neuroendocrine impact (serotonin /5-HT/ and adiponectin) under standardized clinical conditions in an overweight cohort. Adiponectin was measured in serum and Serotonin was determined in the second morning urine samples. Serotonin correlated positively with adiponectin in our investigation Srho (+0.303; p=0.03). As high adiponectin level corresponds with a low risk of Insulin resistance our findings refer to possible improvement of prediabetic conditions in overweight patients tracking peripheral serotonin circulation. Further clinical evidence is mandatory to verify the effects of 5-HT in patients with metabolic syndrome
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