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Novel properties of antimicrobial peptide anoplin
B. Jindřichová, L. Burketová, Z. Novotná,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- amidy chemie farmakologie MeSH
- antifungální látky chemie farmakologie MeSH
- Ascomycota účinky léků MeSH
- Brassica napus genetika mikrobiologie MeSH
- kationické antimikrobiální peptidy chemie farmakologie MeSH
- nemoci rostlin mikrobiologie prevence a kontrola MeSH
- regulace genové exprese u rostlin účinky léků MeSH
- vosí jedy chemie farmakologie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Antimicrobial decapeptide anoplin was tested for its antifungal activity against plant pathogen Leptosphaeria maculans and protection of Brassica napus plants from disease. To reveal the mode of action of the peptide, a natural form of anoplin amidated on C-terminus (ANP-NH2), and its carboxylated analog (ANP-OH) were used in the study. We demonstrated strong antifungal activity of anoplin in vitro regardless C-terminus modification. In addition we show that both ANP-NH2 and ANP-OH induce expression of defence genes in B. napus and protects plants from L. maculans infection. The results indicate that the amidation of anoplin is not essential for its antifungal and plant defence stimulating activities.
Citace poskytuje Crossref.org
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- $a Jindřichová, Barbora $u Institute of Experimental Botany, Czech Academy of Science, Rozvojová 313, 165 02 Prague 6, Czech Republic; Department of Biochemistry and Microbiology, Institute of Chemical Technology Prague, Technická 5, 165 21 Prague 6, Czech Republic.
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- $a Antimicrobial decapeptide anoplin was tested for its antifungal activity against plant pathogen Leptosphaeria maculans and protection of Brassica napus plants from disease. To reveal the mode of action of the peptide, a natural form of anoplin amidated on C-terminus (ANP-NH2), and its carboxylated analog (ANP-OH) were used in the study. We demonstrated strong antifungal activity of anoplin in vitro regardless C-terminus modification. In addition we show that both ANP-NH2 and ANP-OH induce expression of defence genes in B. napus and protects plants from L. maculans infection. The results indicate that the amidation of anoplin is not essential for its antifungal and plant defence stimulating activities.
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- $a Burketová, Lenka $u Institute of Experimental Botany, Czech Academy of Science, Rozvojová 313, 165 02 Prague 6, Czech Republic. Electronic address: burketova@ueb.cas.cz.
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