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Polyphenolic extracts of edible flowers incorporated onto atelocollagen matrices and their effect on cell viability
J. López-García, Z. Kuceková, P. Humpolíček, J. Mlček, P. Sáha,
Language English Country Switzerland
Document type Journal Article, Research Support, Non-U.S. Gov't
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- MeSH
- Cell Line MeSH
- Collagen chemistry MeSH
- Flowers chemistry MeSH
- Humans MeSH
- Cell Line, Tumor MeSH
- Polyphenols chemistry pharmacology MeSH
- Cell Proliferation drug effects MeSH
- Plant Extracts chemistry pharmacology MeSH
- Tissue Engineering MeSH
- Cell Survival MeSH
- Chromatography, High Pressure Liquid MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
The phenolic extract of chives flowers (Allium schoenoprasum, Liliaceae), introduced Sage (Salvia pratensis, Lamiaceae), European elderberry (Sambucus nigra, Caprifoliaceae) and common dandelion (Taraxacum officinale, Asteraceae) were characterised by High Performance Liquid Chromatography and incorporated in different concentrations onto atelocollagen thin films. In order to assess the biological impact of these phenolic compounds on cell viability, human immortalised non-tumorigenic keratinocyte cell line was seeded on the thin films and cell proliferation was determined by using an MTT assay. In addition, their antimicrobial activity was estimated by using an agar diffusion test. Data indicated the concomitance between cell viability and concentration of polyphenols. These findings suggest that these phenolic-endowed atelocollagen films might be suitable for tissue engineering applications, on account of the combined activity of polyphenols and collagen.
References provided by Crossref.org
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