-
Something wrong with this record ?
Numerical analysis of non-Newtonian blood flow and wall shear stress in realistic single, double and triple aorto-coronary bypasses
J. Vimmr, A. Jonášová, O. Bublík,
Language English Country England, Great Britain
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
23733715
DOI
10.1002/cnm.2560
Knihovny.cz E-resources
- MeSH
- Algorithms MeSH
- Hemodynamics physiology MeSH
- Coronary Artery Bypass methods MeSH
- Coronary Vessels surgery MeSH
- Humans MeSH
- Stress, Mechanical MeSH
- Blood Flow Velocity physiology MeSH
- Models, Theoretical MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
Considering the fact that hemodynamics plays an important role in the patency and overall performance of implanted bypass grafts, this work presents a numerical investigation of pulsatile non-Newtonian blood flow in three different patient-specific aorto-coronary bypasses. The three bypass models are distinguished from each other by the number of distal side-to-side and end-to-side anastomoses and denoted as single, double and triple bypasses. The mathematical model in the form of time-dependent nonlinear system of incompressible Navier-Stokes equations is coupled with the Carreau-Yasuda model describing the shear-thinning property of human blood and numerically solved using the principle of the SIMPLE algorithm and cell-centred finite volume method formulated for hybrid unstructured tetrahedral grids. The numerical results computed for non-Newtonian and Newtonian blood flow in the three aorto-coronary bypasses are compared and analysed with emphasis placed on the distribution of cycle-averaged wall shear stress and oscillatory shear index. As shown in this study, the non-Newtonian blood flow in all of the considered bypass models does not significantly differ from the Newtonian one. Our observations further suggest that, especially in the case of sequential grafts, the resulting flow field and shear stimulation are strongly influenced by the diameter of the vessels involved in the bypassing.
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc14064156
- 003
- CZ-PrNML
- 005
- 20140710112042.0
- 007
- ta
- 008
- 140704s2013 enk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1002/cnm.2560 $2 doi
- 035 __
- $a (PubMed)23733715
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a Vimmr, J $u European Centre of Excellence NTIS - New Technologies for Information Society, Faculty of Applied Sciences, University of West Bohemia, Pilsen, Czech Republic.
- 245 10
- $a Numerical analysis of non-Newtonian blood flow and wall shear stress in realistic single, double and triple aorto-coronary bypasses / $c J. Vimmr, A. Jonášová, O. Bublík,
- 520 9_
- $a Considering the fact that hemodynamics plays an important role in the patency and overall performance of implanted bypass grafts, this work presents a numerical investigation of pulsatile non-Newtonian blood flow in three different patient-specific aorto-coronary bypasses. The three bypass models are distinguished from each other by the number of distal side-to-side and end-to-side anastomoses and denoted as single, double and triple bypasses. The mathematical model in the form of time-dependent nonlinear system of incompressible Navier-Stokes equations is coupled with the Carreau-Yasuda model describing the shear-thinning property of human blood and numerically solved using the principle of the SIMPLE algorithm and cell-centred finite volume method formulated for hybrid unstructured tetrahedral grids. The numerical results computed for non-Newtonian and Newtonian blood flow in the three aorto-coronary bypasses are compared and analysed with emphasis placed on the distribution of cycle-averaged wall shear stress and oscillatory shear index. As shown in this study, the non-Newtonian blood flow in all of the considered bypass models does not significantly differ from the Newtonian one. Our observations further suggest that, especially in the case of sequential grafts, the resulting flow field and shear stimulation are strongly influenced by the diameter of the vessels involved in the bypassing.
- 650 _2
- $a algoritmy $7 D000465
- 650 _2
- $a rychlost toku krve $x fyziologie $7 D001783
- 650 _2
- $a koronární bypass $x metody $7 D001026
- 650 _2
- $a koronární cévy $x chirurgie $7 D003331
- 650 _2
- $a hemodynamika $x fyziologie $7 D006439
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a teoretické modely $7 D008962
- 650 _2
- $a mechanický stres $7 D013314
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Jonášová, A
- 700 1_
- $a Bublík, O
- 773 0_
- $w MED00184043 $t International journal for numerical methods in biomedical engineering $x 2040-7947 $g Roč. 29, č. 10 (2013), s. 1057-81
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/23733715 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20140704 $b ABA008
- 991 __
- $a 20140710112334 $b ABA008
- 999 __
- $a ok $b bmc $g 1031640 $s 862888
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2013 $b 29 $c 10 $d 1057-81 $i 2040-7947 $m International journal for numerical methods in biomedical engineering $n Int j numer method biomed eng $x MED00184043
- LZP __
- $a Pubmed-20140704