• Something wrong with this record ?

Numerical analysis of non-Newtonian blood flow and wall shear stress in realistic single, double and triple aorto-coronary bypasses

J. Vimmr, A. Jonášová, O. Bublík,

. 2013 ; 29 (10) : 1057-81.

Language English Country England, Great Britain

Document type Journal Article, Research Support, Non-U.S. Gov't

Considering the fact that hemodynamics plays an important role in the patency and overall performance of implanted bypass grafts, this work presents a numerical investigation of pulsatile non-Newtonian blood flow in three different patient-specific aorto-coronary bypasses. The three bypass models are distinguished from each other by the number of distal side-to-side and end-to-side anastomoses and denoted as single, double and triple bypasses. The mathematical model in the form of time-dependent nonlinear system of incompressible Navier-Stokes equations is coupled with the Carreau-Yasuda model describing the shear-thinning property of human blood and numerically solved using the principle of the SIMPLE algorithm and cell-centred finite volume method formulated for hybrid unstructured tetrahedral grids. The numerical results computed for non-Newtonian and Newtonian blood flow in the three aorto-coronary bypasses are compared and analysed with emphasis placed on the distribution of cycle-averaged wall shear stress and oscillatory shear index. As shown in this study, the non-Newtonian blood flow in all of the considered bypass models does not significantly differ from the Newtonian one. Our observations further suggest that, especially in the case of sequential grafts, the resulting flow field and shear stimulation are strongly influenced by the diameter of the vessels involved in the bypassing.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc14064156
003      
CZ-PrNML
005      
20140710112042.0
007      
ta
008      
140704s2013 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1002/cnm.2560 $2 doi
035    __
$a (PubMed)23733715
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Vimmr, J $u European Centre of Excellence NTIS - New Technologies for Information Society, Faculty of Applied Sciences, University of West Bohemia, Pilsen, Czech Republic.
245    10
$a Numerical analysis of non-Newtonian blood flow and wall shear stress in realistic single, double and triple aorto-coronary bypasses / $c J. Vimmr, A. Jonášová, O. Bublík,
520    9_
$a Considering the fact that hemodynamics plays an important role in the patency and overall performance of implanted bypass grafts, this work presents a numerical investigation of pulsatile non-Newtonian blood flow in three different patient-specific aorto-coronary bypasses. The three bypass models are distinguished from each other by the number of distal side-to-side and end-to-side anastomoses and denoted as single, double and triple bypasses. The mathematical model in the form of time-dependent nonlinear system of incompressible Navier-Stokes equations is coupled with the Carreau-Yasuda model describing the shear-thinning property of human blood and numerically solved using the principle of the SIMPLE algorithm and cell-centred finite volume method formulated for hybrid unstructured tetrahedral grids. The numerical results computed for non-Newtonian and Newtonian blood flow in the three aorto-coronary bypasses are compared and analysed with emphasis placed on the distribution of cycle-averaged wall shear stress and oscillatory shear index. As shown in this study, the non-Newtonian blood flow in all of the considered bypass models does not significantly differ from the Newtonian one. Our observations further suggest that, especially in the case of sequential grafts, the resulting flow field and shear stimulation are strongly influenced by the diameter of the vessels involved in the bypassing.
650    _2
$a algoritmy $7 D000465
650    _2
$a rychlost toku krve $x fyziologie $7 D001783
650    _2
$a koronární bypass $x metody $7 D001026
650    _2
$a koronární cévy $x chirurgie $7 D003331
650    _2
$a hemodynamika $x fyziologie $7 D006439
650    _2
$a lidé $7 D006801
650    _2
$a teoretické modely $7 D008962
650    _2
$a mechanický stres $7 D013314
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Jonášová, A
700    1_
$a Bublík, O
773    0_
$w MED00184043 $t International journal for numerical methods in biomedical engineering $x 2040-7947 $g Roč. 29, č. 10 (2013), s. 1057-81
856    41
$u https://pubmed.ncbi.nlm.nih.gov/23733715 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20140704 $b ABA008
991    __
$a 20140710112334 $b ABA008
999    __
$a ok $b bmc $g 1031640 $s 862888
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2013 $b 29 $c 10 $d 1057-81 $i 2040-7947 $m International journal for numerical methods in biomedical engineering $n Int j numer method biomed eng $x MED00184043
LZP    __
$a Pubmed-20140704

Find record

Citation metrics

Loading data ...

Archiving options

Loading data ...