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Clinical studies monitoring circulating and disseminated tumor cells in gastrointestinal cancers

P. Eliasova, K. Kolostova, C. Kobierzycki, V. Bobek,

. 2013 ; 51 (4) : 265-277.

Language English Country Poland

Document type Journal Article, Research Support, Non-U.S. Gov't, Review

Persistent link   https://www.medvik.cz/link/bmc14074291

Grant support
NT14439 MZ0 CEP Register

Circulating tumor cells (CTCs) and disseminated tumor cells (DTCs) are responsible for the development of metastatic disease, and may also hold the key to determining tailored therapies of advanced cancer disease. Our review summarizes the prognostic significance of the detection of CTCs and DTCs in various gastrointestinal cancers with an overview of their possible use as prognostic biomarkers. This could be used inthe future as a starting point for new clinical trials focusing on the predictive potential of circulating and disseminated tumor cells.

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