Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Heavy metals in hair samples: a pilot study of anaemic children in Kazakhstan, Kyrgyzstan and Uzbekistan

Z. Derflerová Brázdová, J. Pomerleau, J. Fiala, L. Vorlová, D. Müllerová

. 2014 ; 22 (4) : 273-276.

Language English Country Czech Republic

Document type Journal Article, Research Support, Non-U.S. Gov't

Persistent link   https://www.medvik.cz/link/bmc15008879

BACKGROUND: Heavy metals with their potential haematotoxic effect can contribute to the risks of anaemia in children in the Central Asian Republics (CAR), where burden and exposure to these metals is still not sufficiently known and reported. METHODS: Cross-sectional study was performed in Central Asian countries in hospitals in Kazakhstan, Kyrgyzstan and Uzbekistan with the aim to investigate the potential contribution of heavy metals to anaemia in children. In each country, 20 children were recruited, all were hospitalised with diagnosed anaemia. A sample of hair was taken from each child to assess the hair concentration of lead, cadmium and mercury. RESULTS: Relatively high levels of hair lead were observed, particularly in Kyrgyzstan. While lead and cadmium concentrations did not differ significantly among countries, mercury was lower in Kazakhstan than in Kyrgyzstan (p < 0.05) and Uzbekistan (p < 0.001). Hair lead and cadmium levels were significantly positively correlated (correlation coefficient = 0.51, p < 0.001). CONCLUSION: The results of this study showed higher than expected levels of hair lead, cadmium and mercury in anaemic children. Because iron deficiency anaemia is a major public health problem in CAR, further investigation of the extent of exposure to heavy metal and its contribution in iron deficiency anaemia in the region would be recommended.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc15008879
003      
CZ-PrNML
005      
20150312084238.0
007      
ta
008      
150305s2014 xr f 000 0|eng||
009      
AR
024    7_
$a 10.21101/cejph.a4003 $2 doi
035    __
$a (PubMed)25622488
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Brázdová, Zuzana, $d 1957- $7 mzk2002113251 $u Department of Preventive Medicine, Faculty of Medicine, Masaryk University, Brno, Czech Republic
245    10
$a Heavy metals in hair samples: a pilot study of anaemic children in Kazakhstan, Kyrgyzstan and Uzbekistan / $c Z. Derflerová Brázdová, J. Pomerleau, J. Fiala, L. Vorlová, D. Müllerová
520    9_
$a BACKGROUND: Heavy metals with their potential haematotoxic effect can contribute to the risks of anaemia in children in the Central Asian Republics (CAR), where burden and exposure to these metals is still not sufficiently known and reported. METHODS: Cross-sectional study was performed in Central Asian countries in hospitals in Kazakhstan, Kyrgyzstan and Uzbekistan with the aim to investigate the potential contribution of heavy metals to anaemia in children. In each country, 20 children were recruited, all were hospitalised with diagnosed anaemia. A sample of hair was taken from each child to assess the hair concentration of lead, cadmium and mercury. RESULTS: Relatively high levels of hair lead were observed, particularly in Kyrgyzstan. While lead and cadmium concentrations did not differ significantly among countries, mercury was lower in Kazakhstan than in Kyrgyzstan (p < 0.05) and Uzbekistan (p < 0.001). Hair lead and cadmium levels were significantly positively correlated (correlation coefficient = 0.51, p < 0.001). CONCLUSION: The results of this study showed higher than expected levels of hair lead, cadmium and mercury in anaemic children. Because iron deficiency anaemia is a major public health problem in CAR, further investigation of the extent of exposure to heavy metal and its contribution in iron deficiency anaemia in the region would be recommended.
650    _2
$a mladiství $7 D000293
650    _2
$a anemie z nedostatku železa $x epidemiologie $7 D018798
650    _2
$a kadmium $x analýza $7 D002104
650    _2
$a dítě $7 D002648
650    _2
$a předškolní dítě $7 D002675
650    _2
$a průřezové studie $7 D003430
650    _2
$a vystavení vlivu životního prostředí $x škodlivé účinky $x analýza $7 D004781
650    _2
$a látky znečišťující životní prostředí $x analýza $x toxicita $7 D004785
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a vlasy, chlupy $x chemie $7 D006197
650    _2
$a hemoglobiny $7 D006454
650    _2
$a lidé $7 D006801
650    _2
$a olovo $x analýza $7 D007854
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a rtuť $x analýza $7 D008628
650    _2
$a těžké kovy $x analýza $7 D019216
650    _2
$a pilotní projekty $7 D010865
651    _2
$a střední Asie $x epidemiologie $7 D001209
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Pomerleau, Joceline $u Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom
700    1_
$a Fiala, Jindřich, $d 1959- $7 nlk20010099061 $u Department of Preventive Medicine, Faculty of Medicine, Masaryk University, Brno, Czech Republic
700    1_
$a Vorlová, Lenka $7 ola2004212066 $u Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic
700    1_
$a Müllerová, Dana, $d 1962- $7 xx0011940 $u Department of Public Health, Medical Faculty in Pilsen, Charles University, Pilsen, Czech Republic
773    0_
$w MED00001083 $t Central European journal of public health $x 1210-7778 $g Roč. 22, č. 4 (2014), s. 273-276
856    41
$u http://apps.szu.cz/svi/cejph/ $y Domovská stránka časopisu
910    __
$a ABA008 $b B 1829 $c 562 $y 4 $z 0
990    __
$a 20150305 $b ABA008
991    __
$a 20150310085516 $b ABA008
999    __
$a ok $b bmc $g 1066837 $s 891682
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2014 $b 22 $c 4 $d 273-276 $i 1210-7778 $m Central European Journal of Public Health $n Cent. Eur. J. Public Health $x MED00001083
LZP    __
$b NLK118 $a Pubmed-20150305

Find record

Citation metrics

Archiving options