• Je něco špatně v tomto záznamu ?

Endovascular treatment of acute basilar artery occlusion: time to treatment is crucial

T. Dorňák, R. Herzig, M. Kuliha, R. Havlíček, D. Školoudík, D. Šaňák, M. Köcher, V. Procházka, J. Lacman, F. Charvát, A. Krajina, D. Krajíčková, M. Král, T. Veverka, M. Roubec, L. Hajduková, J. Zapletalová,

. 2015 ; 70 (5) : e20-7.

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články, multicentrická studie, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc15022809

Grantová podpora
NT11046 MZ0 CEP - Centrální evidence projektů

AIM: To evaluate the safety and efficacy of multimodal endovascular treatment (EVT) of acute basilar artery occlusion (BAO), including bridging therapy [intravenous thrombolysis (IVT) with subsequent EVT], to compare particular EVT techniques and identify predictors of clinical outcome. MATERIALS AND METHODS: This retrospective, multi-centre study comprised 72 acute ischaemic stroke patients (51 males; mean age 59.1 ± 13.3 years) with radiologically confirmed BAO. The following data were collected: baseline characteristics, risk factors, pre-event antithrombotic treatment, neurological deficit at time of treatment, localization of occlusion, time to therapy, recanalization rate, post-treatment imaging findings. Thirty- and 90-day outcomes were evaluated using the modified Rankin scale with a good clinical outcome defined as 0-3 points. RESULTS: Successful recanalization was achieved in 94.4% patients. Stepwise binary logistic regression analysis identified the presence of arterial hypertension (OR = 0.073 and OR = 0.067, respectively), National Institutes of Health Stroke Scale (NIHSS) at the time of treatment (OR = 0,829 and OR = 0.864, respectively), and time to treatment (OR = 0.556 and OR = 0.502, respectively) as significant independent predictors of 30- and 90-day clinical outcomes. CONCLUSION: Data from this multicentre study showed that multimodal EVT was an effective recanalization method in acute BAO. Bridging therapy shortens the time to treatment, which was identified as the only modifiable outcome predictor.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc15022809
003      
CZ-PrNML
005      
20240131091122.0
007      
ta
008      
150709s2015 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.crad.2015.01.008 $2 doi
035    __
$a (PubMed)25703459
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Dorňák, Tomáš $u Department of Neurology, Palacký University, Olomouc, Czech Republic; Comprehensive Stroke Center, Department of Neurology, University Hospital Olomouc, Czech Republic. $7 xx0228515
245    10
$a Endovascular treatment of acute basilar artery occlusion: time to treatment is crucial / $c T. Dorňák, R. Herzig, M. Kuliha, R. Havlíček, D. Školoudík, D. Šaňák, M. Köcher, V. Procházka, J. Lacman, F. Charvát, A. Krajina, D. Krajíčková, M. Král, T. Veverka, M. Roubec, L. Hajduková, J. Zapletalová,
520    9_
$a AIM: To evaluate the safety and efficacy of multimodal endovascular treatment (EVT) of acute basilar artery occlusion (BAO), including bridging therapy [intravenous thrombolysis (IVT) with subsequent EVT], to compare particular EVT techniques and identify predictors of clinical outcome. MATERIALS AND METHODS: This retrospective, multi-centre study comprised 72 acute ischaemic stroke patients (51 males; mean age 59.1 ± 13.3 years) with radiologically confirmed BAO. The following data were collected: baseline characteristics, risk factors, pre-event antithrombotic treatment, neurological deficit at time of treatment, localization of occlusion, time to therapy, recanalization rate, post-treatment imaging findings. Thirty- and 90-day outcomes were evaluated using the modified Rankin scale with a good clinical outcome defined as 0-3 points. RESULTS: Successful recanalization was achieved in 94.4% patients. Stepwise binary logistic regression analysis identified the presence of arterial hypertension (OR = 0.073 and OR = 0.067, respectively), National Institutes of Health Stroke Scale (NIHSS) at the time of treatment (OR = 0,829 and OR = 0.864, respectively), and time to treatment (OR = 0.556 and OR = 0.502, respectively) as significant independent predictors of 30- and 90-day clinical outcomes. CONCLUSION: Data from this multicentre study showed that multimodal EVT was an effective recanalization method in acute BAO. Bridging therapy shortens the time to treatment, which was identified as the only modifiable outcome predictor.
650    _2
$a arteriální okluzní nemoci $x diagnóza $x terapie $7 D001157
650    12
$a arteria basilaris $7 D001488
650    _2
$a kombinovaná terapie $7 D003131
650    _2
$a diagnostické zobrazování $7 D003952
650    12
$a endovaskulární výkony $7 D057510
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé středního věku $7 D008875
650    _2
$a retrospektivní studie $7 D012189
650    _2
$a časové faktory $7 D013997
650    _2
$a výsledek terapie $7 D016896
655    _2
$a časopisecké články $7 D016428
655    _2
$a multicentrická studie $7 D016448
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Herzig, Roman, $u Department of Neurology, Palacký University, Olomouc, Czech Republic; Comprehensive Stroke Center, Department of Neurosurgery, Military University Hospital Prague, Czech Republic. Electronic address: herzig.roman@seznam.cz. $d 1968- $7 mzk2007411122
700    1_
$a Kuliha, Martin $u Comprehensive Stroke Center, Department of Neurology, Ostrava University and University Hospital Ostrava, Czech Republic. $7 xx0313290
700    1_
$a Havlíček, Roman $u Comprehensive Stroke Center, Department of Neurology, Military University Hospital Prague, Czech Republic. $7 xx0230021
700    1_
$a Školoudík, David, $u Department of Neurology, Palacký University, Olomouc, Czech Republic. $d 1972- $7 xx0020614
700    1_
$a Šaňák, Daniel $u Comprehensive Stroke Center, Department of Neurology, University Hospital Olomouc, Czech Republic. $7 xx0104413
700    1_
$a Köcher, Martin $u Comprehensive Stroke Center, Department of Radiology, Palacký University and University Hospital Olomouc, Czech Republic. $7 jn20010309197
700    1_
$a Procházka, Václav $u Comprehensive Stroke Center, Department of Radiology, Ostrava University and University Hospital Ostrava, Czech Republic. $7 xx0070646
700    1_
$a Lacman, Jiří $u Comprehensive Stroke Center, Department of Radiology, Military University Hospital Prague, Czech Republic. $7 xx0061409
700    1_
$a Charvát, František, $u Comprehensive Stroke Center, Department of Radiology, Military University Hospital Prague, Czech Republic. $d 1963- $7 jn20010602633
700    1_
$a Krajina, Antonín, $u Comprehensive Stroke Center, Department of Radiology, Charles University and University Hospital Hradec Králové, Czech Republic. $d 1958- $7 nlk20050172885
700    1_
$a Krajíčková, Dagmar, $u Comprehensive Stroke Center, Department of Neurology, Charles University and University Hospital Hradec Králové, Czech Republic. $d 1948- $7 mzk2005274977
700    1_
$a Král, M $u Department of Neurology, Palacký University, Olomouc, Czech Republic; Comprehensive Stroke Center, Department of Neurology, University Hospital Olomouc, Czech Republic.
700    1_
$a Veverka, Tomáš, $d 1976- $7 xx0215370 $u Department of Neurology, Palacký University, Olomouc, Czech Republic; Comprehensive Stroke Center, Department of Neurology, University Hospital Olomouc, Czech Republic.
700    1_
$a Roubec, Martin $u Comprehensive Stroke Center, Department of Neurology, Ostrava University and University Hospital Ostrava, Czech Republic. $7 xx0231427
700    1_
$a Hajduková, Lenka $u Comprehensive Stroke Center, Department of Neurology, Military University Hospital Prague, Czech Republic. $7 _AN039751
700    1_
$a Zapletalová, Jana $u Department of Medical Biophysics, Palacký University Olomouc, Czech Republic. $7 xx0111614
773    0_
$w MED00009490 $t Clinical radiology $x 1365-229X $g Roč. 70, č. 5 (2015), s. e20-7
856    41
$u https://pubmed.ncbi.nlm.nih.gov/25703459 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20150709 $b ABA008
991    __
$a 20240131091118 $b ABA008
999    __
$a ok $b bmc $g 1083148 $s 905802
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2015 $b 70 $c 5 $d e20-7 $i 1365-229X $m Clinical radiology $n Clin Radiol $x MED00009490
GRA    __
$a NT11046 $p MZ0
LZP    __
$a Pubmed-20150709

Najít záznam

Citační ukazatele

Možnosti archivace