Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Small nucleolar RNAs functioning and potential roles in cancer

N. Thorenoor, O. Slaby,

. 2015 ; 36 (1) : 41-53.

Language English Country Netherlands

Document type Journal Article, Research Support, Non-U.S. Gov't, Review

Persistent link   https://www.medvik.cz/link/bmc15022925

Non-coding RNAs (ncRNAs) are important regulatory molecules involved in various physiological and pathological cellular processes. Small nucleolar RNAs (snoRNAs), subclass of small ncRNAs, have been considered important but unglamorous elements in the production of protein synthesis machinery of cells. However, recent evidence has indicated that these non-coding RNAs might have a crucial role also in controlling cell behavior, and snoRNAs dysfunction could significantly contribute to carcinogenesis. Here, we summarize the most important aspects of snoRNAs biology, their functioning in cancer cell, and potential usage in diagnosis or as a new class of therapeutic targets in cancer.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc15022925
003      
CZ-PrNML
005      
20150723102410.0
007      
ta
008      
150709s2015 ne f 000 0|eng||
009      
AR
024    7_
$a 10.1007/s13277-014-2818-8 $2 doi
035    __
$a (PubMed)25420907
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a ne
100    1_
$a Thorenoor, Nithyananda $u Central European Institute of Technology, Masaryk University, Kamenice 753/5, 62500, Brno, Czech Republic.
245    10
$a Small nucleolar RNAs functioning and potential roles in cancer / $c N. Thorenoor, O. Slaby,
520    9_
$a Non-coding RNAs (ncRNAs) are important regulatory molecules involved in various physiological and pathological cellular processes. Small nucleolar RNAs (snoRNAs), subclass of small ncRNAs, have been considered important but unglamorous elements in the production of protein synthesis machinery of cells. However, recent evidence has indicated that these non-coding RNAs might have a crucial role also in controlling cell behavior, and snoRNAs dysfunction could significantly contribute to carcinogenesis. Here, we summarize the most important aspects of snoRNAs biology, their functioning in cancer cell, and potential usage in diagnosis or as a new class of therapeutic targets in cancer.
650    _2
$a alternativní sestřih $7 D017398
650    _2
$a zvířata $7 D000818
650    _2
$a sekvence nukleotidů $7 D001483
650    _2
$a regulace genové exprese u nádorů $7 D015972
650    _2
$a lidé $7 D006801
650    _2
$a cílená molekulární terapie $7 D058990
650    _2
$a nádory $x genetika $x metabolismus $x terapie $7 D009369
650    _2
$a RNA interference $7 D034622
650    _2
$a posttranskripční úpravy RNA $7 D012323
650    _2
$a malá jadérková RNA $x fyziologie $7 D020537
650    _2
$a fyziologický stres $7 D013312
650    _2
$a nádorové biomarkery $x fyziologie $7 D014408
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
655    _2
$a přehledy $7 D016454
700    1_
$a Slaby, Ondrej
773    0_
$w MED00008757 $t Tumour biology the journal of the International Society for Oncodevelopmental Biology and Medicine $x 1423-0380 $g Roč. 36, č. 1 (2015), s. 41-53
856    41
$u https://pubmed.ncbi.nlm.nih.gov/25420907 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20150709 $b ABA008
991    __
$a 20150723102448 $b ABA008
999    __
$a ok $b bmc $g 1083264 $s 905918
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2015 $b 36 $c 1 $d 41-53 $i 1423-0380 $m Tumor biology $n Tumor Biol $x MED00008757
LZP    __
$a Pubmed-20150709

Find record

Citation metrics

Archiving options