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The role of Six1 in the genesis of muscle cell and skeletal muscle development

W. Wu, R. Huang, Q. Wu, P. Li, J. Chen, B. Li, H. Liu,

. 2014 ; 10 (9) : 983-9.

Jazyk angličtina Země Austrálie

Typ dokumentu časopisecké články, práce podpořená grantem, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc15023039

The sine oculis homeobox 1 (Six1) gene encodes an evolutionarily conserved transcription factor. In the past two decades, much research has indicated that Six1 is a powerful regulator participating in skeletal muscle development. In this review, we summarized the discovery and structural characteristics of Six1 gene, and discussed the functional roles and molecular mechanisms of Six1 in myogenesis and in the formation of skeletal muscle fibers. Finally, we proposed areas of future interest for understanding Six1 gene function.

Citace poskytuje Crossref.org

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