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Daily profiles of dehydroepiandrosterone and its hydroxylated metabolites with respect to food intake

L. Stárka, B. Rácz, M. Šrámková, M. Hill, M. Dušková

. 2015 ; 116 (1) : 40-48.

Language English Country Czech Republic

Document type Journal Article, Research Support, Non-U.S. Gov't

Persistent link   https://www.medvik.cz/link/bmc15026878

Grant support
NT12340 MZ0 CEP Register

Eight women of reproductive age with normal body mass index were given 5 standardised meals, and their hormonal milieu was determined during the course of the day. Plasma from 12 withdrawals was analysed for dehydroepiandrosterone and its 7- and 16-hydroxylated metabolites. Overall, there was a maximum in the levels of steroid hormones in the morning, followed by decreases throughout the day. There was also an additional significant decrease found for dehydroepiandrosterone and its 7α-hydroxyderivative in association with the consumption of main meals, but not for the 7β-isomer or 16α-hydroxyderivative.

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