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Macrotetrolide antibiotics produced by Streptomyces globisporus
J. Jizba, P. Sedmera, J. Zima, M. Beran, M. Blumauerová, NV. Kandybin, GV. Samoukina,
Language English Country Czech Republic
Document type Journal Article
PubMed
1821868
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents biosynthesis chemistry pharmacology MeSH
- Pest Control, Biological MeSH
- Coleoptera MeSH
- Insecticides chemistry metabolism MeSH
- Macrolides MeSH
- Molecular Structure MeSH
- Streptomyces metabolism MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
Macrotetrolides isolated from a new producer, Streptomyces globisporus, were identified as nonactin, monactin, dinactin and trinactin. Spectroscopic characterization of these compounds was extended by 13NMR spectra. Chemical ionization with ammonia as reactive gas was proposed for mass-spectroscopic characterization of their mixtures. Their biological activity was confirmed by using larvae of the Colorado potato beetle (Leptinotarsa decemlineata) as a new test model.
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- $a Macrotetrolides isolated from a new producer, Streptomyces globisporus, were identified as nonactin, monactin, dinactin and trinactin. Spectroscopic characterization of these compounds was extended by 13NMR spectra. Chemical ionization with ammonia as reactive gas was proposed for mass-spectroscopic characterization of their mixtures. Their biological activity was confirmed by using larvae of the Colorado potato beetle (Leptinotarsa decemlineata) as a new test model.
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