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A Deep Insight Into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera)
JM. Ribeiro, A. Schwarz, IM. Francischetti,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, Research Support, N.I.H., Extramural, práce podpořená grantem
PubMed
26334808
DOI
10.1093/jme/tjv023
Knihovny.cz E-zdroje
- MeSH
- fylogeneze MeSH
- hmyzí proteiny genetika metabolismus MeSH
- molekulární sekvence - údaje MeSH
- nymfa genetika růst a vývoj metabolismus MeSH
- Panstrongylus genetika růst a vývoj metabolismus MeSH
- proteomika MeSH
- sialoglykoproteiny genetika metabolismus MeSH
- slinné proteiny a peptidy genetika metabolismus MeSH
- sliny chemie MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Research Support, N.I.H., Extramural MeSH
Saliva of blood-sucking arthropods contains a complex cocktail of pharmacologically active compounds that assists feeding by counteracting their hosts' hemostatic and inflammatory reactions. Panstrongylus megistus (Burmeister) is an important vector of Chagas disease in South America, but despite its importance there is only one salivary protein sequence publicly deposited in GenBank. In the present work, we used Illumina technology to disclose and publicly deposit 3,703 coding sequences obtained from the assembly of >70 million reads. These sequences should assist proteomic experiments aimed at identifying pharmacologically active proteins and immunological markers of vector exposure. A supplemental file of the transcriptome and deducted protein sequences can be obtained from http://exon.niaid.nih.gov/transcriptome/P_megistus/Pmeg-web.xlsx.
Citace poskytuje Crossref.org
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