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Fluorescence imaging for specific analysis of cancer cells

Iva Blažková, Markéta Vaculovičová, Vojtěch Adam, René Kizek

. 2015 ; 2 (2) : 48-52.

Jazyk angličtina Země Česko

Typ dokumentu přehledy, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc16016294

Cancer is a serious disease that causes 25% of deaths in the developed countries. Significant impact on the cancer patients survival has early detection of this disease, therefore great attention is paid to its imaging. Fluorescence imaging represents powerful imaging method for the cell detection. For the successful detection of tumour cells, the specific targeting of fluorescence probes to the tumour tissue has a key role. Interesting materials enabling the imaging of tumour cells are fluorescence nanoparticles. For the accurate imaging, the NPs should be conjugated with targeting ligands and/or constructed as off-on probes.

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$a Cancer is a serious disease that causes 25% of deaths in the developed countries. Significant impact on the cancer patients survival has early detection of this disease, therefore great attention is paid to its imaging. Fluorescence imaging represents powerful imaging method for the cell detection. For the successful detection of tumour cells, the specific targeting of fluorescence probes to the tumour tissue has a key role. Interesting materials enabling the imaging of tumour cells are fluorescence nanoparticles. For the accurate imaging, the NPs should be conjugated with targeting ligands and/or constructed as off-on probes.
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