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Cervical Lymph Node Metastasis in High-Grade Transformation of Head and Neck Adenoid Cystic Carcinoma: A Collective International Review
H. Hellquist, A. Skálová, L. Barnes, A. Cardesa, LD. Thompson, A. Triantafyllou, MD. Williams, KO. Devaney, DR. Gnepp, JA. Bishop, BM. Wenig, C. Suárez, JP. Rodrigo, A. Coca-Pelaz, P. Strojan, JP. Shah, M. Hamoir, PJ. Bradley, CE. Silver, PJ....
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, přehledy
- MeSH
- adenoidně cystický karcinom mortalita patologie chirurgie MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- lymfatické metastázy patologie MeSH
- lymfatické uzliny patologie MeSH
- nádory slinných žláz mortalita patologie chirurgie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Adenoid cystic carcinoma (AdCC) is among the most common malignant tumors of the salivary glands. It is characterized by a prolonged clinical course, with frequent local recurrences, late onset of metastases and fatal outcome. High-grade transformation (HGT) is an uncommon phenomenon among salivary carcinomas and is associated with increased tumor aggressiveness. In AdCC with high-grade transformation (AdCC-HGT), the clinical course deviates from the natural history of AdCC. It tends to be accelerated, with a high propensity for lymph node metastasis. In order to shed light on this rare event and, in particular, on treatment implications, we undertook this review: searching for all published cases of AdCC-HGT. We conclude that it is mandatory to perform elective neck dissection in patients with AdCC-HGT, due to the high risk of lymph node metastases associated with transformation.
Coordinator of the International Head and Neck Scientific Group Padua Italy
Department of Anatomic Pathology Hospital Clinic University of Barcelona Barcelona Spain
Department of Biomedical Sciences and Medicine University of Algarve Faro Portugal
Department of Otolaryngology Head and Neck Surgery Philipp University Marburg Germany
Department of Otolaryngology Hospital Universitario Central de Asturias Oviedo Spain
Department of Pathology Allegiance Health Jackson MI USA
Department of Pathology Beth Israel Medical Center New York NY USA
Department of Pathology Faculty of Medicine in Plzen Charles University Prague Plzen Czech Republic
Department of Pathology Radboud University Medical Center Nijmegen The Netherlands
Department of Pathology The University of Texas MD Anderson Cancer Center Houston TX USA
Department of Pathology University of Pittsburgh School of Medicine Pittsburgh PA USA
Department of Radiation Oncology Institute of Oncology Ljubljana Slovenia
Department of Radiation Oncology University of Florida Gainesville FL USA
Department of Surgery Banner MD Anderson Cancer Center Gilbert AZ USA
Head and Neck Surgery Memorial Sloan Kettering Cancer Center New York NY USA
Southern California Permanente Medical Group Woodland Hills CA USA
University of Udine School of Medicine Udine Italy
University Pathologists Providence RI USA University Pathologists Fall River MA USA
Citace poskytuje Crossref.org
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