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Early Diagnosis of Cutaneous Mucormycosis Due to Lichtheimia corymbifera After a Traffic Accident
T. Tyll, P. Lyskova, V. Hubka, M. Muller, L. Zelenka, M. Curdova, I. Tuckova, M. Kolarik, P. Hamal,
Language English Country Netherlands
Document type Case Reports, Journal Article
NLK
ProQuest Central
from 1997-04-01 to 1 year ago
Medline Complete (EBSCOhost)
from 2011-01-01 to 1 year ago
Health & Medicine (ProQuest)
from 1997-04-01 to 1 year ago
- MeSH
- Amphotericin B administration & dosage MeSH
- Antifungal Agents administration & dosage MeSH
- Early Diagnosis MeSH
- Debridement MeSH
- DNA, Fungal chemistry genetics MeSH
- Accidents, Traffic MeSH
- Adult MeSH
- Histocytochemistry MeSH
- Wound Infection diagnosis microbiology pathology MeSH
- Humans MeSH
- DNA, Ribosomal Spacer chemistry genetics MeSH
- Microscopy MeSH
- Mucorales classification genetics isolation & purification MeSH
- Mucormycosis diagnosis microbiology pathology MeSH
- Wounds and Injuries complications MeSH
- Sequence Analysis, DNA MeSH
- Treatment Outcome MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
A case report of cutaneous mucormycosis and obstacles to early diagnosis is presented. A 38-year-old male was involved in a car accident that led to amputation of both lower limbs. Subsequently, he developed fungal wound infection of the left lower limb stump. The infection was detected very early, although the diagnosis was difficult because only a small area was affected and histopathological examination was initially negative. The infection was proven by microscopy, culture and histopathology. The isolate was identified by sequencing of the rDNA ITS region gene (internal transcribed spacer region of ribosomal DNA) as Lichtheimia corymbifera. Liposomal amphotericin B and surgery were successful in management of the disease.
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- $a Tyll, Tomas $u Department of Anesthesiology, Resuscitation and Intensive Care Medicine, First Faculty of Medicine, Charles University in Prague and the Military University Hospital Prague, U Vojenske Nemocnice 1200, 169 02, Prague 6, Czech Republic.
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- $a Early Diagnosis of Cutaneous Mucormycosis Due to Lichtheimia corymbifera After a Traffic Accident / $c T. Tyll, P. Lyskova, V. Hubka, M. Muller, L. Zelenka, M. Curdova, I. Tuckova, M. Kolarik, P. Hamal,
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- $a A case report of cutaneous mucormycosis and obstacles to early diagnosis is presented. A 38-year-old male was involved in a car accident that led to amputation of both lower limbs. Subsequently, he developed fungal wound infection of the left lower limb stump. The infection was detected very early, although the diagnosis was difficult because only a small area was affected and histopathological examination was initially negative. The infection was proven by microscopy, culture and histopathology. The isolate was identified by sequencing of the rDNA ITS region gene (internal transcribed spacer region of ribosomal DNA) as Lichtheimia corymbifera. Liposomal amphotericin B and surgery were successful in management of the disease.
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- $a Hubka, Vit $u Department of Botany, Faculty of Science, Charles University in Prague, Benatska 2, 128 01, Praha 2, Czech Republic. Laboratory of Fungal Genetics and Metabolism, Institute of Microbiology of the AS CR, Videnska 1083, 142 20, Praha 4, Czech Republic. First Faculty of Medicine, Charles University in Prague, Katerinska 32, 121 08, Prague 2, Czech Republic.
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