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Early Diagnosis of Cutaneous Mucormycosis Due to Lichtheimia corymbifera After a Traffic Accident

Tyll, Tomas
Autor Tyll, Tomas Department of Anesthesiology, Resuscitation and Intensive Care Medicine, First Faculty of Medicine, Charles University in Prague and the Military University Hospital Prague, U Vojenske Nemocnice 1200, 169 02, Prague 6, Czech Republic
Lyskova, Pavlina
Autor Lyskova, Pavlina Laboratory of Medical Mycology, Department of Parasitology, Mycology and Mycobacteriology Prague, Public Health Institute in Usti nad Labem, Sokolovska 60, 186 00, Prague 8, Czech Republic. pavlina.lyskova@zuusti.cz Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Hnevotinska 3, 77515, Olomouc, Czech Republic. pavlina.lyskova@zuusti.cz
Hubka, Vit
Autor Hubka, Vit Department of Botany, Faculty of Science, Charles University in Prague, Benatska 2, 128 01, Praha 2, Czech Republic Laboratory of Fungal Genetics and Metabolism, Institute of Microbiology of the AS CR, Videnska 1083, 142 20, Praha 4, Czech Republic First Faculty of Medicine, Charles University in Prague, Katerinska 32, 121 08, Prague 2, Czech Republic
Muller, Martin
Autor Muller, Martin Department of Anesthesiology, Resuscitation and Intensive Care Medicine, First Faculty of Medicine, Charles University in Prague and the Military University Hospital Prague, U Vojenske Nemocnice 1200, 169 02, Prague 6, Czech Republic
Zelenka, Lubomir
Autor Zelenka, Lubomir Department of Orthopaedics, First Faculty of Medicine, Charles University in Prague and the Military University Hospital Prague, U Vojenske Nemocnice 1200, 169 02, Prague 6, Czech Republic
Curdova, Martina
Autor Curdova, Martina Department of Clinical Microbiology, Military University Hospital Prague, U Vojenske Nemocnice 1200, 169 02, Prague 6, Czech Republic
Tuckova, Inna
Autor Tuckova, Inna Department of Pathology, Military University Hospital Prague, U Vojenske Nemocnice 1200, 169 02, Prague 6, Czech Republic
Kolarik, Miroslav
Autor Kolarik, Miroslav Department of Botany, Faculty of Science, Charles University in Prague, Benatska 2, 128 01, Praha 2, Czech Republic Laboratory of Fungal Genetics and Metabolism, Institute of Microbiology of the AS CR, Videnska 1083, 142 20, Praha 4, Czech Republic
Hamal, Petr
Autor Hamal, Petr Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Hnevotinska 3, 77515, Olomouc, Czech Republic

Mycopathologia. 2016 Feb ; 181 (1-2) : 119-24. [epub] 20150912

ISSN 1573-0832 | 0301-486X
Zdroj

Jazyk angličtina Země Nizozemsko Médium print-electronic

Typ dokumentu kazuistiky, časopisecké články

Perzistentní odkaz https://www.medvik.cz/link/pmid26363921

PubMed 26363921
DOI 10.1007/s11046-015-9943-9
PII: 10.1007/s11046-015-9943-9
Knihovny.cz E-zdroje

Klíčová slova
Amphotericin B, Cutaneous mucormycosis, Lichtheimia corymbifera, Mycological diagnosis,
MeSH
amfotericin B aplikace a dávkování MeSH
antifungální látky aplikace a dávkování MeSH
časná diagnóza MeSH
debridement MeSH
DNA fungální chemie genetika MeSH
dopravní nehody MeSH
dospělí MeSH
histocytochemie MeSH
infekce v ráně diagnóza mikrobiologie patologie MeSH
lidé MeSH
mezerníky ribozomální DNA chemie genetika MeSH
mikroskopie MeSH
Mucorales klasifikace genetika izolace a purifikace MeSH
mukormykóza diagnóza mikrobiologie patologie MeSH
rány a poranění komplikace MeSH
sekvenční analýza DNA MeSH
výsledek terapie MeSH
Check Tag
dospělí MeSH
lidé MeSH
mužské pohlaví MeSH
Publikační typ
časopisecké články MeSH
kazuistiky MeSH
Názvy látek
amfotericin B MeSH
antifungální látky MeSH
DNA fungální MeSH
liposomal amphotericin B MeSH Prohlížeč
mezerníky ribozomální DNA MeSH

A case report of cutaneous mucormycosis and obstacles to early diagnosis is presented. A 38-year-old male was involved in a car accident that led to amputation of both lower limbs. Subsequently, he developed fungal wound infection of the left lower limb stump. The infection was detected very early, although the diagnosis was difficult because only a small area was affected and histopathological examination was initially negative. The infection was proven by microscopy, culture and histopathology. The isolate was identified by sequencing of the rDNA ITS region gene (internal transcribed spacer region of ribosomal DNA) as Lichtheimia corymbifera. Liposomal amphotericin B and surgery were successful in management of the disease.

1st Faculty of Medicine Charles University Prague Katerinska 32 121 08 Prague 2 Czech Republic

Department of Anesthesiology Resuscitation and Intensive Care Medicine 1st Faculty of Medicine Charles University Prague and the Military University Hospital Prague U Vojenske Nemocnice 1200 169 02 Prague 6 Czech Republic

Department of Botany Faculty of Science Charles University Prague Benatska 2 128 01 Praha 2 Czech Republic

Department of Clinical Microbiology Military University Hospital Prague U Vojenske Nemocnice 1200 169 02 Prague 6 Czech Republic

Department of Microbiology Faculty of Medicine and Dentistry Palacky University Olomouc Hnevotinska 3 77515 Olomouc Czech Republic

Department of Orthopaedics 1st Faculty of Medicine Charles University Prague and the Military University Hospital Prague U Vojenske Nemocnice 1200 169 02 Prague 6 Czech Republic

Department of Pathology Military University Hospital Prague U Vojenske Nemocnice 1200 169 02 Prague 6 Czech Republic

Laboratory of Fungal Genetics and Metabolism Institute of Microbiology of the AS CR Videnska 1083 142 20 Praha 4 Czech Republic

Laboratory of Medical Mycology Department of Parasitology Mycology and Mycobacteriology Prague Public Health Institute in Usti nad Labem Sokolovska 60 186 00 Prague 8 Czech Republic

Zobrazit více v PubMed

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