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Temporal variation selects for diet-microbe co-metabolic traits in the gut of Gorilla spp
A. Gomez, JM. Rothman, K. Petrzelkova, CJ. Yeoman, K. Vlckova, JD. Umaña, M. Carr, D. Modry, A. Todd, M. Torralba, KE. Nelson, RM. Stumpf, BA. Wilson, R. Blekhman, BA. White, SR. Leigh,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, práce podpořená grantem
NLK
PubMed Central
od 2011
Europe PubMed Central
od 2011 do Před 1 rokem
ProQuest Central
od 2007-05-01 do Před 1 rokem
Health & Medicine (ProQuest)
od 2007-05-01 do Před 1 rokem
Oxford Journals Open Access Collection
od 2007
ROAD: Directory of Open Access Scholarly Resources
od 2007
PubMed
26315972
DOI
10.1038/ismej.2015.146
Knihovny.cz E-zdroje
- MeSH
- Bacteria klasifikace genetika izolace a purifikace MeSH
- biologická evoluce MeSH
- druhová specificita MeSH
- feces mikrobiologie MeSH
- gastrointestinální trakt metabolismus mikrobiologie MeSH
- Gorilla gorilla metabolismus mikrobiologie MeSH
- krmivo pro zvířata analýza MeSH
- potravní vláknina metabolismus MeSH
- střevní mikroflóra * MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Although the critical role that our gastrointestinal microbes play in host physiology is now well established, we know little about the factors that influenced the evolution of primate gut microbiomes. To further understand current gut microbiome configurations and diet-microbe co-metabolic fingerprints in primates, from an evolutionary perspective, we characterized fecal bacterial communities and metabolomic profiles in 228 fecal samples of lowland and mountain gorillas (G. g. gorilla and G. b. beringei, respectively), our closest evolutionary relatives after chimpanzees. Our results demonstrate that the gut microbiomes and metabolomes of these two species exhibit significantly different patterns. This is supported by increased abundance of metabolites and bacterial taxa associated with fiber metabolism in mountain gorillas, and enrichment of markers associated with simple sugar, lipid and sterol turnover in the lowland species. However, longitudinal sampling shows that both species' microbiomes and metabolomes converge when hosts face similar dietary constraints, associated with low fruit availability in their habitats. By showing differences and convergence of diet-microbe co-metabolic fingerprints in two geographically isolated primate species, under specific dietary stimuli, we suggest that dietary constraints triggered during their adaptive radiation were potential factors behind the species-specific microbiome patterns observed in primates today.
Department of Animal and Range Sciences Montana State University Bozeman MT USA
J Craig Venter Institute Rockville MD USA
World Wildlife Fund Dzanga Sangha Protected Areas Bayanga Central African Republic
Citace poskytuje Crossref.org
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