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Leptospirosis-Associated Severe Pulmonary Hemorrhagic Syndrome with Lower Back Pain as an Initial Symptom
MM. Søndergaard, A. Tursunovic, P. Thye-Rønn, JC. Bang, IM. Hansen,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu kazuistiky, časopisecké články
NLK
Free Medical Journals
od 2008
PubMed Central
od 2012
Europe PubMed Central
od 2012
Open Access Digital Library
od 2012-01-01
PubMed
27881835
DOI
10.12659/ajcr.900477
Knihovny.cz E-zdroje
- MeSH
- diferenciální diagnóza MeSH
- DNA bakterií analýza MeSH
- hemoptýza diagnóza etiologie MeSH
- Leptospira genetika MeSH
- leptospiróza komplikace mikrobiologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- lumbalgie diagnóza etiologie MeSH
- rentgendiagnostika hrudníku MeSH
- stupeň závažnosti nemoci MeSH
- syndrom MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
BACKGROUND Leptospirosis is a zoonosis transmitted through urine of infected animals. Symptoms range from mild influenza-like symptoms to severe pulmonary hemorrhagic syndrome (SPHS); the latter are often fatal. The serogroup distribution in Denmark has changed from 1988 to 2012, with Icterohaemorrhagiae and Sejroe now being predominant. CASE REPORT A 45-year-old Danish woman living in an area endemic for Hanta virus, without prior medical history, was admitted because of lower back pain radiating to the left hip, fever, headache, nausea, and malaise. Two weeks before admission she had been bitten by a mouse or a rat. Blood tests revealed raised white cells and CRP, electrolyte imbalances, raised creatinine, low thrombocytes, and a slightly decreased clotting factor (II, VII, and X). Treatment with broad-spectrum intravenous antibiotics and supporting therapy was initiated very quickly. Eight hours after admission she died from respiratory failure where severe hemoptysis was observed. Leptospiral DNA was later detected in a urine sample. CONCLUSIONS This case represents leptospirosis with severe pulmonary hemorrhagic syndrome. In spite of immediate treatment with broad-spectrum antibiotics, the patient died a few hours after hospital admission.
Department of Cardiology Odense University Hospital Svendborg Hospital Svendborg Denmark
Department of Radiology Odense University Hospital Svendborg Hospital Svendborg Czech Republic
Department of Rheumatology Odense University Hospital Svendborg Hospital Svendborg Denmark
Diagnostic Center Odense University Hospital Svendborg Hospital Svendborg Denmark
Citace poskytuje Crossref.org
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- $a BACKGROUND Leptospirosis is a zoonosis transmitted through urine of infected animals. Symptoms range from mild influenza-like symptoms to severe pulmonary hemorrhagic syndrome (SPHS); the latter are often fatal. The serogroup distribution in Denmark has changed from 1988 to 2012, with Icterohaemorrhagiae and Sejroe now being predominant. CASE REPORT A 45-year-old Danish woman living in an area endemic for Hanta virus, without prior medical history, was admitted because of lower back pain radiating to the left hip, fever, headache, nausea, and malaise. Two weeks before admission she had been bitten by a mouse or a rat. Blood tests revealed raised white cells and CRP, electrolyte imbalances, raised creatinine, low thrombocytes, and a slightly decreased clotting factor (II, VII, and X). Treatment with broad-spectrum intravenous antibiotics and supporting therapy was initiated very quickly. Eight hours after admission she died from respiratory failure where severe hemoptysis was observed. Leptospiral DNA was later detected in a urine sample. CONCLUSIONS This case represents leptospirosis with severe pulmonary hemorrhagic syndrome. In spite of immediate treatment with broad-spectrum antibiotics, the patient died a few hours after hospital admission.
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