The identification of a novel HLA-B*35:279 allele in a Czech patient is described. This allele is identical to the B*35:03:01 variant except the G/A nucleotide exchange at position 652 of the HLA-B gene that corresponds to the amino acid substitution from valine to isoleucine in alpha 3 domain of the HLA-B antigen.

Department of Hemato Oncology University Hospital and Faculty of Medicine and Dentistry Palacky University Olomouc Czech Republic

Department of HLA Institute of Hematology and Blood Transfusion Prague Czech Republic

Department of Immunology University Hospital and Faculty of Medicine and Dentistry Palacky University Olomouc Czech Republic

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$a Mrázek, František, $u Department of Immunology, University Hospital and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. $d 1973- $7 xx0051697

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$a A novel HLA-B allele, HLA-B*35:279, identified by sequencing-based typing in a Czech patient / $c F. Mrazek, J. Onderkova, N. Königova, V. Siffnerova, M. Vrana, Z. Ambruzova, I. Skoumalova, M. Petrek, L. Raida,

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$a The identification of a novel HLA-B*35:279 allele in a Czech patient is described. This allele is identical to the B*35:03:01 variant except the G/A nucleotide exchange at position 652 of the HLA-B gene that corresponds to the amino acid substitution from valine to isoleucine in alpha 3 domain of the HLA-B antigen.

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$a Onderková, Jana $u Department of Immunology, University Hospital and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. $7 xx0159689

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$a Königova, N $u Department of Immunology, University Hospital and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

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$a Šiffnerová, Věra $u Department of HLA, Institute of Hematology and Blood Transfusion, Prague, Czech Republic. $7 xx0217369

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$a Vrana, M $u Department of HLA, Institute of Hematology and Blood Transfusion, Prague, Czech Republic.

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$a Ambruzova, Z $u Department of Immunology, University Hospital and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. $7 gn_A_00005477

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$a Skoumalova, I $u Department of Hemato-Oncology, University Hospital and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

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$a Petřek, Martin, $u Department of Immunology, University Hospital and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. $d 1963- $7 jn20000401972

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$a Raida, Luděk, $u Department of Hemato-Oncology, University Hospital and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. $d 1968- $7 xx0034365

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$w MED00008484 $t International journal of immunogenetics $x 1744-313X $g Roč. 43, č. 4 (2016), s. 246-248

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