Nowadays, biomedicine is characterised by a growing need for processing of large amounts of data in real time. This leads to new requirements for information and communication technologies (ICT). Cloud computing offers a solution to these requirements and provides many advantages, such as cost savings, elasticity and scalability of using ICT. The aim of this paper is to explore the concept of cloud computing and the related use of this concept in the area of biomedicine. Authors offer a comprehensive analysis of the implementation of the cloud computing approach in biomedical research, decomposed into infrastructure, platform and service layer, and a recommendation for processing large amounts of data in biomedicine. Firstly, the paper describes the appropriate forms and technological solutions of cloud computing. Secondly, the high-end computing paradigm of cloud computing aspects is analysed. Finally, the potential and current use of applications in scientific research of this technology in biomedicine is discussed.

Faculty of Informatics and Management University of Hradec Kralove Rokitanského 62 Hradec Kralove 50003 Czech Republic

Faculty of Informatics and Management University of Hradec Kralove Rokitanského 62 Hradec Kralove 50003 Czech Republic b Laboratory of Molecular Modeling Applied to the Chemical and Biological Defense Military Institute of Engineering Rio de Janeiro 22290 270 RJ Brazil c Department of Chemistry and Biochemistry Concordia University Montreal QC Canada

Faculty of Informatics and Management University of Hradec Kralove Rokitanského 62 Hradec Kralove 50003 Czech Republic b Laboratory of Molecular Modeling Applied to the Chemical and Biological Defense Military Institute of Engineering Rio de Janeiro 22290 270 RJ Brazil d Biomedical Research Center University Hospital Hradec Kralove Hradec Kralove Czech Republic

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