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Needleless coaxial electrospinning: A novel approach to mass production of coaxial nanofibers
L. Vysloužilová, M. Buzgo, P. Pokorný, J. Chvojka, A. Míčková, M. Rampichová, J. Kula, K. Pejchar, M. Bílek, D. Lukáš, E. Amler,
Language English Country Netherlands
Document type Journal Article
Grant support
NV16-29680A
MZ0
CEP Register
NV16-29680A
MZ0
CEP Register
- MeSH
- Technology, Pharmaceutical methods MeSH
- Drug Delivery Systems * MeSH
- Delayed-Action Preparations MeSH
- Humans MeSH
- Nanofibers * MeSH
- Regenerative Medicine methods MeSH
- Tissue Engineering methods MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
Herein, we describe a simple spinneret setup for needleless coaxial electrospinning that exceeds the limited production capacity of current approaches. The proposed weir spinneret enables coaxial electrospinning from free liquid surface. This approach leads to the formation of coaxial nanofibers with higher and uniform shell/core ratio, which results in the possibility of better tuning of the degradation rate. The throughput and quality increase favor the broader application of coaxial nanofibers from weir spinnerets as systems for controlled drug delivery in regenerative medicine and tissue engineering.
Department of Nonwovens Technical University of Liberec Studentska 2 461 17 Liberec Czechia
Department of Textile Evaluation Technical University of Liberec Studentska 2 461 17 Liberec Czechia
References provided by Crossref.org
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- $a Herein, we describe a simple spinneret setup for needleless coaxial electrospinning that exceeds the limited production capacity of current approaches. The proposed weir spinneret enables coaxial electrospinning from free liquid surface. This approach leads to the formation of coaxial nanofibers with higher and uniform shell/core ratio, which results in the possibility of better tuning of the degradation rate. The throughput and quality increase favor the broader application of coaxial nanofibers from weir spinnerets as systems for controlled drug delivery in regenerative medicine and tissue engineering.
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- $a Buzgo, Matej $u Department of Biophysics, 2nd Faculty of Medicine, Charles University in Prague, V Úvalu 84, 150 06, Prague 5, Czechia; Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, v.v.i., Vídeňská 1083, 142 20, Prague 4, Czechia; University Centre for Energy Efiicient Buildings, Czech Technical University in Prague, Trinecka 1024, 273 43, Bustehrad, Czechia. Electronic address: buzgo@labdemo.cz.
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