• Je něco špatně v tomto záznamu ?

Feasibility of In-Vivo Simulation of Acute Hemodynamics in Human Atrial Fibrillation

M. Sramko, D. Wichterle, J. Kautzner,

. 2016 ; 11 (10) : e0165241. [pub] 20161020

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc17023611

This study evaluated hemodynamic feasibility and reproducibility of a new method for in vivo simulation of human atrial fibrillation (AF). The method was tested during sinus rhythm in 10 patients undergoing catheter ablation for AF. A simple electronic device was assembled that allowed triggering a cardiac stimulator by predefined series of RR intervals. Irregular RR interval sequences with a mean heart rate of 90/min and 130/min were obtained from ECG recordings of another patients with AF. Simultaneous atrioventricular pacing was delivered by catheters placed inside the coronary sinus and at the His bundle region. Hemodynamic effect of the simulated AF was assessed by invasive measurement of the left ventricular (LV) pressure, dP/dt, and Tau. Compared to regular pacing at the same mean heart rate, the simulated AF significantly impaired the LV both systolic and diastolic function. Repeated AF pacing in the same patients generated similar LV hemodynamics. The proposed method provides a realistic and reproducible in-vivo model of AF. It can be exploited for investigation of the hemodynamic consequences of AF in various patient populations.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc17023611
003      
CZ-PrNML
005      
20170720122302.0
007      
ta
008      
170720s2016 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1371/journal.pone.0165241 $2 doi
035    __
$a (PubMed)27764240
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Sramko, Marek $u Department of Cardiology, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic.
245    10
$a Feasibility of In-Vivo Simulation of Acute Hemodynamics in Human Atrial Fibrillation / $c M. Sramko, D. Wichterle, J. Kautzner,
520    9_
$a This study evaluated hemodynamic feasibility and reproducibility of a new method for in vivo simulation of human atrial fibrillation (AF). The method was tested during sinus rhythm in 10 patients undergoing catheter ablation for AF. A simple electronic device was assembled that allowed triggering a cardiac stimulator by predefined series of RR intervals. Irregular RR interval sequences with a mean heart rate of 90/min and 130/min were obtained from ECG recordings of another patients with AF. Simultaneous atrioventricular pacing was delivered by catheters placed inside the coronary sinus and at the His bundle region. Hemodynamic effect of the simulated AF was assessed by invasive measurement of the left ventricular (LV) pressure, dP/dt, and Tau. Compared to regular pacing at the same mean heart rate, the simulated AF significantly impaired the LV both systolic and diastolic function. Repeated AF pacing in the same patients generated similar LV hemodynamics. The proposed method provides a realistic and reproducible in-vivo model of AF. It can be exploited for investigation of the hemodynamic consequences of AF in various patient populations.
650    _2
$a senioři $7 D000368
650    _2
$a fibrilace síní $x patofyziologie $x chirurgie $7 D001281
650    _2
$a nodus atrioventricularis $x patofyziologie $7 D001283
650    _2
$a kardiostimulace umělá $7 D002304
650    _2
$a katetrizační ablace $7 D017115
650    _2
$a elektrokardiografie $7 D004562
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a srdce $x diagnostické zobrazování $7 D006321
650    _2
$a srdeční frekvence $7 D006339
650    _2
$a srdeční komory $x patofyziologie $7 D006352
650    12
$a hemodynamika $7 D006439
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé středního věku $7 D008875
655    _2
$a časopisecké články $7 D016428
700    1_
$a Wichterle, Dan $u Department of Cardiology, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic.
700    1_
$a Kautzner, Josef $u Department of Cardiology, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic.
773    0_
$w MED00180950 $t PloS one $x 1932-6203 $g Roč. 11, č. 10 (2016), s. e0165241
856    41
$u https://pubmed.ncbi.nlm.nih.gov/27764240 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20170720 $b ABA008
991    __
$a 20170720122755 $b ABA008
999    __
$a ok $b bmc $g 1239292 $s 984524
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2016 $b 11 $c 10 $d e0165241 $e 20161020 $i 1932-6203 $m PLoS One $n PLoS One $x MED00180950
LZP    __
$a Pubmed-20170720

Najít záznam

Citační ukazatele

Možnosti archivace