• Something wrong with this record ?

New adenoviruses from new primate hosts - growing diversity reveals taxonomic weak points

E. Dadáková, T. Chrudimský, K. Brožová, D. Modrý, V. Celer, K. Hrazdilová,

. 2017 ; 107 (-) : 305-307. [pub] 20161125

Language English Country United States

Document type Journal Article, Research Support, Non-U.S. Gov't

Persistent link   https://www.medvik.cz/link/bmc18016891

The knowledge of the closest human relatives of human adenoviruses (AdVs) such as adenoviruses found in nonhuman primates is still limited, despite the growing importance of adenoviruses in vaccine development, gene and cancer therapy. We examined 153 stool samples of 17 non-human primate species and detected adenoviral DNA sequences of DNA polymerase (DPOL) gene in 54 samples (35%), originating from 12 out of 17 primate species. We further sequenced 15 hexon gene fragments and based on the phylogenetic analysis we propose two new provisional species SAdV-H and SAdV-I. Our study shows extensive diversity of adenoviral strains forming separate clades often from closely related host species from old world monkeys suggesting the existence of new species of AdVs and shows the necessity for clear ICTV guidelines for final establishment of so far provisional AdV species.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc18016891
003      
CZ-PrNML
005      
20180515103424.0
007      
ta
008      
180515s2017 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.ympev.2016.11.013 $2 doi
035    __
$a (PubMed)27894993
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Dadáková, Eva $u Department of Infectious Diseases and Microbiology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic.
245    10
$a New adenoviruses from new primate hosts - growing diversity reveals taxonomic weak points / $c E. Dadáková, T. Chrudimský, K. Brožová, D. Modrý, V. Celer, K. Hrazdilová,
520    9_
$a The knowledge of the closest human relatives of human adenoviruses (AdVs) such as adenoviruses found in nonhuman primates is still limited, despite the growing importance of adenoviruses in vaccine development, gene and cancer therapy. We examined 153 stool samples of 17 non-human primate species and detected adenoviral DNA sequences of DNA polymerase (DPOL) gene in 54 samples (35%), originating from 12 out of 17 primate species. We further sequenced 15 hexon gene fragments and based on the phylogenetic analysis we propose two new provisional species SAdV-H and SAdV-I. Our study shows extensive diversity of adenoviral strains forming separate clades often from closely related host species from old world monkeys suggesting the existence of new species of AdVs and shows the necessity for clear ICTV guidelines for final establishment of so far provisional AdV species.
650    _2
$a opičí adenoviry $x klasifikace $x genetika $7 D000261
650    _2
$a zvířata $7 D000818
650    _2
$a sekvence nukleotidů $7 D001483
650    _2
$a Bayesova věta $7 D001499
650    12
$a genetická variace $7 D014644
650    12
$a interakce hostitele a patogenu $7 D054884
650    _2
$a lidé $7 D006801
650    _2
$a nukleotidy $x genetika $7 D009711
650    _2
$a fylogeneze $7 D010802
650    _2
$a primáti $x virologie $7 D011323
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Chrudimský, Tomáš $u Institute of Soil Biology, Biology Centre, Czech Academy of Sciences, v. v. i., České Budějovice, Czech Republic.
700    1_
$a Brožová, Kristýna $u Department of Infectious Diseases and Microbiology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic.
700    1_
$a Modrý, David $u Department of Pathology and Parasitology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic; Institute of Parasitology, Biology Centre, Czech Academy of Sciences, Czech Republic; CEITEC VFU, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic.
700    1_
$a Celer, Vladimír $u Department of Infectious Diseases and Microbiology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic; CEITEC VFU, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic.
700    1_
$a Hrazdilová, Kristýna $u Department of Virology, Veterinary Research Institute, Czech Republic; CEITEC VFU, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic. Electronic address: kristyna@hrazdilova.cz.
773    0_
$w MED00006574 $t Molecular phylogenetics and evolution $x 1095-9513 $g Roč. 107, č. - (2017), s. 305-307
856    41
$u https://pubmed.ncbi.nlm.nih.gov/27894993 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20180515 $b ABA008
991    __
$a 20180515103558 $b ABA008
999    __
$a ok $b bmc $g 1300515 $s 1013731
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2017 $b 107 $c - $d 305-307 $e 20161125 $i 1095-9513 $m Molecular phylogenetics and evolution $n Mol Phylogenet Evol $x MED00006574
LZP    __
$a Pubmed-20180515

Find record

Citation metrics

Archiving options