-
Something wrong with this record ?
Antimicrobial effect of OKCEL® H-D prepared from oxidized cellulose
P. Moťková, I. Brožková, J. Vytřasová, R. Kukla,
Language English Country United States
Document type Journal Article
- MeSH
- Anti-Bacterial Agents chemistry pharmacology MeSH
- Bacillus subtilis drug effects growth & development MeSH
- Drug Resistance, Bacterial MeSH
- Cellulose, Oxidized chemistry pharmacology MeSH
- Listeria monocytogenes drug effects growth & development MeSH
- Microbial Sensitivity Tests MeSH
- Staphylococcus aureus drug effects growth & development MeSH
- Publication type
- Journal Article MeSH
The antimicrobial effect of OKCEL® H-D, a topical, absorbable hemostatic textile prepared from oxidized cellulose, was tested. Testing by dilution and diffusion methods was conducted on a spectrum of 27 select microorganisms, including also antibiotic-resistant strains. OKCEL® H-D showed inhibitory effects on nearly all tested bacteria. In testing using the dilution suspension method, the majority of bacteria showed decrease in cell density by 7-8 orders of magnitude after just 6 h of exposure. For clinical isolates of antibiotic-resistant strains, a reduction occurred after 24 h of exposure. In testing the antimicrobial effects of OKCEL® H-D by the dilution method was least effective on spore-forming Bacillus subtilis, for which no antimicrobial effect was detected after 48 h, and on Mycobacterium smegmatis, for which the number of cells decreased by four orders of magnitude only after 24 h. By the diffusion method, inhibition zones were recorded for nearly all test microorganisms except for Staphylococcus aureus, M. smegmatis, and Listeria monocytogenes. No growth beneath the tested OKCEL® H-D material was recorded, however, even for the latter-named bacteria strains, which attests to its good inhibitory effect.
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc18026880
- 003
- CZ-PrNML
- 005
- 20180730110106.0
- 007
- ta
- 008
- 180730s2018 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1007/s12223-017-0534-7 $2 doi
- 035 __
- $a (PubMed)28597345
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Moťková, Petra $u Faculty of Chemical Technology, Department of Biological and Biochemical Sciences, University of Pardubice, Studentská 573, 53210, Pardubice, Czech Republic.
- 245 10
- $a Antimicrobial effect of OKCEL® H-D prepared from oxidized cellulose / $c P. Moťková, I. Brožková, J. Vytřasová, R. Kukla,
- 520 9_
- $a The antimicrobial effect of OKCEL® H-D, a topical, absorbable hemostatic textile prepared from oxidized cellulose, was tested. Testing by dilution and diffusion methods was conducted on a spectrum of 27 select microorganisms, including also antibiotic-resistant strains. OKCEL® H-D showed inhibitory effects on nearly all tested bacteria. In testing using the dilution suspension method, the majority of bacteria showed decrease in cell density by 7-8 orders of magnitude after just 6 h of exposure. For clinical isolates of antibiotic-resistant strains, a reduction occurred after 24 h of exposure. In testing the antimicrobial effects of OKCEL® H-D by the dilution method was least effective on spore-forming Bacillus subtilis, for which no antimicrobial effect was detected after 48 h, and on Mycobacterium smegmatis, for which the number of cells decreased by four orders of magnitude only after 24 h. By the diffusion method, inhibition zones were recorded for nearly all test microorganisms except for Staphylococcus aureus, M. smegmatis, and Listeria monocytogenes. No growth beneath the tested OKCEL® H-D material was recorded, however, even for the latter-named bacteria strains, which attests to its good inhibitory effect.
- 650 _2
- $a antibakteriální látky $x chemie $x farmakologie $7 D000900
- 650 _2
- $a Bacillus subtilis $x účinky léků $x růst a vývoj $7 D001412
- 650 _2
- $a celulosa oxidovaná $x chemie $x farmakologie $7 D002483
- 650 _2
- $a bakteriální léková rezistence $7 D024881
- 650 _2
- $a Listeria monocytogenes $x účinky léků $x růst a vývoj $7 D008089
- 650 _2
- $a mikrobiální testy citlivosti $7 D008826
- 650 _2
- $a Staphylococcus aureus $x účinky léků $x růst a vývoj $7 D013211
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Brožková, Iveta $u Faculty of Chemical Technology, Department of Biological and Biochemical Sciences, University of Pardubice, Studentská 573, 53210, Pardubice, Czech Republic. iveta.brozkova@upce.cz.
- 700 1_
- $a Vytřasová, Jarmila $u Faculty of Chemical Technology, Department of Biological and Biochemical Sciences, University of Pardubice, Studentská 573, 53210, Pardubice, Czech Republic.
- 700 1_
- $a Kukla, Rudolf $u Faculty of Chemical Technology, Department of Biological and Biochemical Sciences, University of Pardubice, Studentská 573, 53210, Pardubice, Czech Republic. Department of Clinical Microbiology, University Hospital, Sokolovská 581, 50003, Hradec Králové, Czech Republic.
- 773 0_
- $w MED00011005 $t Folia microbiologica $x 1874-9356 $g Roč. 63, č. 1 (2018), s. 57-62
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/28597345 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20180730 $b ABA008
- 991 __
- $a 20180730110416 $b ABA008
- 999 __
- $a ok $b bmc $g 1322106 $s 1023811
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2018 $b 63 $c 1 $d 57-62 $e 20170608 $i 1874-9356 $m Folia microbiologica $n Folia microbiol. (Prague) $x MED00011005
- LZP __
- $a Pubmed-20180730