-
Je něco špatně v tomto záznamu ?
Impact of stress on the gut microbiome of free-ranging western lowland gorillas
K. Vlčková, K. Shutt-Phillips, M. Heistermann, B. Pafčo, KJ. Petrželková, A. Todd, D. Modrý, KE. Nelson, BA. Wilson, RM. Stumpf, BA. White, SR. Leigh, A. Gomez,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články
PubMed
29205130
DOI
10.1099/mic.0.000587
Knihovny.cz E-zdroje
- MeSH
- Bacteria klasifikace genetika MeSH
- DNA bakterií MeSH
- feces chemie mikrobiologie MeSH
- fyziologický stres * MeSH
- glukokortikoidy analýza MeSH
- Gorilla gorilla mikrobiologie fyziologie MeSH
- RNA ribozomální 16S MeSH
- sekvenční analýza DNA MeSH
- statistické modely MeSH
- střevní mikroflóra fyziologie MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
Exposure to stressors can negatively impact the mammalian gastrointestinal microbiome (GIM). Here, we used 454 pyrosequencing of 16S rRNA bacterial gene amplicons to evaluate the impact of physiological stress, as evidenced by faecal glucocorticoid metabolites (FGCM; ng/g), on the GIM composition of free-ranging western lowland gorillas (Gorilla gorilla gorilla). Although we found no relationship between GIM alpha diversity (H) and FGCM levels, we observed a significant relationship between the relative abundances of particular bacterial taxa and FGCM levels. Specifically, members of the family Anaerolineaceae (ρ=0.4, FDR q=0.01), genus Clostridium cluster XIVb (ρ=0.35, FDR q=0.02) and genus Oscillibacter (ρ=0.35, FDR q=0.02) were positively correlated with FGCM levels. Thus, while exposure to stressors appears to be associated with minor changes in the gorilla GIM, the consequences of these changes are unknown. Our results may have implications for conservation biology as well as for our overall understanding of factors influencing the non-human primate GIM.
Department of Animal Science University of Minnesota 1364 Eckles Aneue St Paul MN 55108 6118 USA
Fauna and Flora International Pembroke Street Cambridge CB2 3QZ UK
German Primate Centre Endocrinology Laboratory Kellnerweg 4 37077 Göttingen Germany
WWF Dzanga Sangha Protected Areas BP 1053 Bangui Central African Republic
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc19001054
- 003
- CZ-PrNML
- 005
- 20190122125057.0
- 007
- ta
- 008
- 190107s2018 enk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1099/mic.0.000587 $2 doi
- 035 __
- $a (PubMed)29205130
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a Vlčková, Klára $u 1Department of Pathology and Parasitology, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1946/1, Brno 61242, Czech Republic. 2Institute of Vertebrate Biology, Czech Academy of Sciences, Květná 8, Brno 60365, Czech Republic.
- 245 10
- $a Impact of stress on the gut microbiome of free-ranging western lowland gorillas / $c K. Vlčková, K. Shutt-Phillips, M. Heistermann, B. Pafčo, KJ. Petrželková, A. Todd, D. Modrý, KE. Nelson, BA. Wilson, RM. Stumpf, BA. White, SR. Leigh, A. Gomez,
- 520 9_
- $a Exposure to stressors can negatively impact the mammalian gastrointestinal microbiome (GIM). Here, we used 454 pyrosequencing of 16S rRNA bacterial gene amplicons to evaluate the impact of physiological stress, as evidenced by faecal glucocorticoid metabolites (FGCM; ng/g), on the GIM composition of free-ranging western lowland gorillas (Gorilla gorilla gorilla). Although we found no relationship between GIM alpha diversity (H) and FGCM levels, we observed a significant relationship between the relative abundances of particular bacterial taxa and FGCM levels. Specifically, members of the family Anaerolineaceae (ρ=0.4, FDR q=0.01), genus Clostridium cluster XIVb (ρ=0.35, FDR q=0.02) and genus Oscillibacter (ρ=0.35, FDR q=0.02) were positively correlated with FGCM levels. Thus, while exposure to stressors appears to be associated with minor changes in the gorilla GIM, the consequences of these changes are unknown. Our results may have implications for conservation biology as well as for our overall understanding of factors influencing the non-human primate GIM.
- 650 _2
- $a zvířata $7 D000818
- 650 _2
- $a Bacteria $x klasifikace $x genetika $7 D001419
- 650 _2
- $a DNA bakterií $7 D004269
- 650 _2
- $a feces $x chemie $x mikrobiologie $7 D005243
- 650 _2
- $a střevní mikroflóra $x fyziologie $7 D000069196
- 650 _2
- $a glukokortikoidy $x analýza $7 D005938
- 650 _2
- $a Gorilla gorilla $x mikrobiologie $x fyziologie $7 D006071
- 650 _2
- $a statistické modely $7 D015233
- 650 _2
- $a RNA ribozomální 16S $7 D012336
- 650 _2
- $a sekvenční analýza DNA $7 D017422
- 650 12
- $a fyziologický stres $7 D013312
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Shutt-Phillips, Kathryn $u 3Fauna and Flora International, Pembroke Street, Cambridge, CB2 3QZ, UK.
- 700 1_
- $a Heistermann, Michael $u 4German Primate Centre, Endocrinology Laboratory, Kellnerweg 4, 37077 Göttingen, Germany.
- 700 1_
- $a Pafčo, Barbora $u 1Department of Pathology and Parasitology, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1946/1, Brno 61242, Czech Republic.
- 700 1_
- $a Petrželková, Klára J $u 2Institute of Vertebrate Biology, Czech Academy of Sciences, Květná 8, Brno 60365, Czech Republic. 5Liberec Zoo, Masarykova 1347/31, Liberec, 46001, Czech Republic. 6Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Branišovská 31, České Budějovice, 37005, Czech Republic.
- 700 1_
- $a Todd, Angelique $u 7WWF, Dzanga Sangha Protected Areas, BP 1053 Bangui, Central African Republic.
- 700 1_
- $a Modrý, David $u 1Department of Pathology and Parasitology, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1946/1, Brno 61242, Czech Republic. 6Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Branišovská 31, České Budějovice, 37005, Czech Republic. 8CEITEC VFU, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1946/1, Brno, 61242, Czech Republic.
- 700 1_
- $a Nelson, Karen E $u 9J. Craig Venter Institute, 9714 Medical Center Drive, Rockville, MD 20850, USA. 10J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, CA 92037, USA.
- 700 1_
- $a Wilson, Brenda A $u 11Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 West Gregory Drive, Urbana, IL 61801, USA. 12Department of Microbiology, University of Illinois at Urbana-Champaign, 601 South Goodwin Avenue, Urbana, IL 61801, USA.
- 700 1_
- $a Stumpf, Rebecca M $u 12Department of Microbiology, University of Illinois at Urbana-Champaign, 601 South Goodwin Avenue, Urbana, IL 61801, USA. 13Department of Anthropology, University of Illinois at Urbana-Champaign, 607 South Mathews Avenue, Urbana, IL 61801, USA.
- 700 1_
- $a White, Bryan A $u 11Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 West Gregory Drive, Urbana, IL 61801, USA.
- 700 1_
- $a Leigh, Steven R $u 11Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 West Gregory Drive, Urbana, IL 61801, USA. 14Department of Anthropology, University of Colorado at Boulder, 1350 Pleasant Street, Boulder, CO 80309-0233, USA.
- 700 1_
- $a Gomez, Andres $u 15Department of Animal Science, University of Minnesota, 1364 Eckles Aneue, St Paul, MN 55108-6118, USA.
- 773 0_
- $w MED00003340 $t Microbiology (Reading, England) $x 1465-2080 $g Roč. 164, č. 1 (2018), s. 40-44
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/29205130 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20190107 $b ABA008
- 991 __
- $a 20190122125316 $b ABA008
- 999 __
- $a ok $b bmc $g 1364996 $s 1039177
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2018 $b 164 $c 1 $d 40-44 $e 20171205 $i 1465-2080 $m Microbiology $n Microbiology $x MED00003340
- LZP __
- $a Pubmed-20190107
