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First report of Candida bracarensis in Mexico: hydrolytic enzymes and antifungal susceptibility pattern
RJ. Treviño-Rangel, JF. Espinosa-Pérez, H. Villanueva-Lozano, AM. Montoya, A. Andrade, A. Bonifaz, GM. González,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu kazuistiky, časopisecké články
- MeSH
- antifungální látky farmakologie MeSH
- Candida klasifikace účinky léků enzymologie fyziologie MeSH
- DNA fungální genetika MeSH
- genom fungální MeSH
- hydrolasy metabolismus MeSH
- kandidóza vulvovaginální mikrobiologie MeSH
- lidé MeSH
- mezerníky ribozomální DNA genetika MeSH
- mikrobiální testy citlivosti MeSH
- mikrobiální viabilita účinky léků MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- Geografické názvy
- Mexiko MeSH
Candida bracarensis is an emerging cryptic species within the Candida glabrata clade. To date, little is known about its epidemiology, virulence, and antifungal susceptibility. This study documents the occurrence of C. bracarensis for the first time in Mexico and focuses on its in vitro production of hydrolytic enzymes, as well as antifungal susceptibility to echinocandins. This strain was isolated from a vaginal swab of a female with vulvovaginal candidosis; exhibited a very strong activity of aspartyl proteinase, phospholipase, and hemolysin; and was susceptible to caspofungin, anidulafungin, and micafungin (MIC = 0.031 μg/mL). Data obtained could contribute to the knowledge of the epidemiology and virulence attributes of this yeast as a fungal opportunistic human pathogen.
Citace poskytuje Crossref.org
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