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Serum and intratesticular sex steroids in azoospermic men: how do they correlate
J. Heráček, V. Sobotka, L. Kolátorová, J. Kočárek, R. Hampl
Language English Country Czech Republic
Document type Journal Article
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- MeSH
- Azoospermia blood diagnosis MeSH
- Biomarkers blood MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Gonadal Steroid Hormones blood MeSH
- Spermatogenesis physiology MeSH
- Testis metabolism MeSH
- Testosterone blood MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
Five intratesticular sex steroids (testosterone, dihydrotestosterone, androstenedione, estradiol and epitestosterone) along with six serum hormones (LH, FSH, prolactin, SHBG, testosterone and estradiol) were determined in 84 non-obstructive azoospermic men, in order to evaluate to what extent serum and testicular tissue as well as individual hormones in the same material mutually correlate. With exception of androstenedione, tight correlations were found among tissue content of sex steroids, while only weak correlation was recorded between serum and testicular concentrations of major sex steroids testosterone and estradiol. It points to importance of measurement of intratesticular steroids in combination with examination of sperm parameters for assessment of testicular function and spermatogenesis.
References provided by Crossref.org
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