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Workflow for bioprinting of cell-laden bioink
Sebastian Allig, Margot Mayer, Christiane Thielemann
Jazyk angličtina Země Česko
- MeSH
- biokompatibilní materiály chemická syntéza izolace a purifikace terapeutické užití MeSH
- biomedicínské technologie MeSH
- bioprinting * metody přístrojové vybavení MeSH
- buněčné kultury MeSH
- fluorescenční mikroskopie MeSH
- lidé MeSH
- orgánové kultury - kultivační techniky MeSH
- techniky in vitro MeSH
- tkáňové inženýrství * metody přístrojové vybavení MeSH
- Check Tag
- lidé MeSH
Applying technologies of additive manufacturing to the field of tissue engineering created a pioneering new approach to model complex cell systems artificially. Regarding its huge potential, bioprinting is still in its infancies and many questions are still unanswered. To address this issue, an extrusion-based bioprinting (EBB) process was used to deposit human embryonic kidney (HEK) cells in a defined pattern. It was shown that the bioprinted construct featured a high degree in viability reaching up to 77% 10 days after printing (DAP). This work displays a proof of principle for a controlled cell formation which shall later be applied to in vitro drug screening tests using various types of cells.
Literatura
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- $a Applying technologies of additive manufacturing to the field of tissue engineering created a pioneering new approach to model complex cell systems artificially. Regarding its huge potential, bioprinting is still in its infancies and many questions are still unanswered. To address this issue, an extrusion-based bioprinting (EBB) process was used to deposit human embryonic kidney (HEK) cells in a defined pattern. It was shown that the bioprinted construct featured a high degree in viability reaching up to 77% 10 days after printing (DAP). This work displays a proof of principle for a controlled cell formation which shall later be applied to in vitro drug screening tests using various types of cells.
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